Evidence map›Paper›PMID 42269590›Full record

ArticleCell genomics2026

Duplicate, diversify, repeat: The evolution of NOTCH2NL.

Nachshon Egyes, David Gokhman

Abstract read
In one paragraph

Article in Cell genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nachshon EgyesDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
David GokhmanDepartment of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: david.gokhman@weizmann.ac.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Segmental duplications are key drivers of evolutionary innovation but are also particularly challenging to study. In this issue, Real et al. resolve the genetic diversity, structural history, and regulatory landscape of the human-specific NOTCH2NL gene family, a likely contributor to human cortical brain expansion.

Indexed as

Evolution, MolecularReceptor, Notch2AnimalsGene DuplicationGenetic VariationHumansIntercellular Signaling Peptides and ProteinsNerve Tissue ProteinsIntercellular Signaling Peptides and ProteinsNerve Tissue ProteinsNOTCH2NLC protein, humanReceptor, Notch2

Identifiers

PMID42269590
PMCPMC13261643

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.