ArticleScandinavian journal of work, environment & health2026
Association between pesticide use and liver injury: A field study in Taiwan.
Article in Scandinavian journal of work, environment & health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesPesticides are crucial for agricultural development but can be harmful to humans. We conducted a study to investigate the association between pesticide use and liver injury.
methodsWe recruited participants ≥40 years from a district with two agricultural regions where water caltrops and mangoes are cultivated. A random sample of 200 residents from each region was selected, and prevalence ratios (PR) for abnormal liver tests were compared.
resultsA total of 331 individuals participated (participation rate: 82.8%), with 151 from the water caltrop region and 180 from the mango region. Most participants were ≥60 years and predominantly female. Pesticide users had a higher risk of abnormal liver tests [PR 1.74, 95% confidence interval (CI) 1.15-2.62]. Stratified analyses showed higher risks among those with a positive HBsAg test (PR 2.50, 95% CI 1.34-4.64) or a positive anti-HCV Ab test (PR 10.61, 95% CI 6.00-18.77). Multivariable analysis identified a positive HBsAg test [adjusted PR (PR
conclusionsPesticide use was associated with a higher risk of liver injury, particularly among upward sprayers and those with hepatitis B or C infection. The proportion of abnormal liver test cases attributable to upward pesticide spraying in this population might be as large as hepatitis B, supporting the importance of pesticide exposure.
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