Evidence map›Paper›PMID 42269112›Full record

ArticleInternational braz j urol : official journal of the Brazilian Society of Urology

Staged Buried Oral Mucosal Strip Urethroplasty for Long-Segment Post-Hypospadias Urethral Strictures: Achieving Functional Recovery and Distal Meatal Preservation.

Yongdong Pan, Song Li, Jinrui Wang, Tao Liang, Jianwen Huang, Zhenghao Dai, Weidong Zhu, Kaile Zhang, Nailong Cao, Kai Ni and 5 more

Abstract read
In one paragraph

Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Editorial Comment: Female Urethroplasty: A Critical Review of Indications, Techniques and Concerns.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yongdong PanDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Song LiDepartment of Urology, Kaifeng 155 Hospital, China RongTong Medical Healthcare Group, Kaifeng City, Henan Province, China.
Jinrui WangShanghai Jiaotong University School of Medicine, Shanghai, China.
Tao LiangDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jianwen HuangDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhenghao DaiDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Weidong ZhuDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Kaile ZhangDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Nailong CaoDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Kai NiDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
E LinDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Sanbao JinDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuemin XuDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qiang FuDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lujie SongDepartment of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLong-segment urethral strictures following hypospadias repair (LUSPH) represent a formidable reconstructive challenge. Few techniques simultaneously achieve durable stricture resolution while preserving the distal urethral meatus. This study evaluates the efficacy, safety, and patient-reported outcomes of staged buried oral mucosal strip urethroplasty for LUSPH. PATIENTS AND

methodsA retrospective analysis was conducted on patients undergoing this procedure between June 2016 and June 2024. Stage one involved inlay of an oral mucosal graft. In the second stage, the healed composite mucosal strip was tubularized using penile fascial flap. Outcomes assessed included maximum flow rate (Qmax), patient-reported outcome measures (USS-PROM, QoL-PROM, IIEF-5), surgical success (defined as unobstructed voiding without intervention, Qmax >15 mL/s, and absence of major complications), and complications.

resultsSixty-one patients were enrolled, with a mean age of 29.8 ± 9.1 years and mean stricture length of 4.7 ± 0.7 cm. Ultimately, 51 patients (83.6%) achieved unobstructed voiding meeting the definition of surgical success. The mean Qmax at 1-year postoperatively was 18.5 ± 4.3 mL/s. From preoperatively to 1-year postoperatively, USS-PROM scores significantly decreased from 21.0 ± 2.0 to 6.6 ± 2.2 (P < 0.001), while QoL-PROM scores significantly improved from 46.6 ± 6.7 to 87.2 ± 8.2 (P < 0.001). IIEF-5 scores showed no significant change. Finally, 54 patients (88.5%) maintained a meatus positioned above the coronal sulcus.

conclusionsIn this single-center retrospective cohort, staged buried oral mucosal strip urethroplasty demonstrated favorable mid-term efficacy and safety for LUSPH.

Indexed as

HypospadiasMouth MucosaPostoperative ComplicationsUrethraUrethral StrictureAdolescentAdultHumansMaleMiddle AgedPatient Reported Outcome MeasuresPlastic Surgery ProceduresRecovery of FunctionRetrospective StudiesSurgical FlapsTreatment OutcomeHypospadiasMouth MucosaUrethral Stricture

Identifiers

PMID42269112
PMCPMC13682753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.