ReviewBiotechnology and bioengineering2026
Biodegradable Polyhydroxyalkanoates as Advanced Antimicrobial Biomaterials: A Review.
Review in Biotechnology and bioengineering, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Biodegradable Polyhydroxyalkanoates as Advanced Antimicrobial Biomaterials: A Review.Biotechnology and bioengineering · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyhydroxyalkanoates (PHA), a class of biodegradable polyesters synthesized by microorganisms, have emerged as a key platform for advanced antimicrobial biomedicine. Distinguished by their exceptional biocompatibility, tunable degradation kinetics and versatile material properties, PHA offer a sustainable, functional alternative to conventional polymers. Furthermore, specific PHA materials exhibit inherent antimicrobial properties, opening new avenues for the developing eco-efficient medical materials. This review systematically outlines the multifaceted antibacterial mechanisms of PHA, including their intrinsic structure-activity relationships, the bioactive roles of their degradation products, and their effectiveness as carriers for engineered antimicrobial agents. Recent advances in PHA-based applications are also critically summarized, with a focus on wound dressings, surgical sutures, orthopaedical implants, and targeted drug delivery systems. The therapeutic performance of these applications in infection control and tissue repair is also highlighted. Finally, this paper discusses the current challenges to translation and propose strategic research directions, aiming to chart a developmental roadmap for the next generation of intelligent, PHA-based, antimicrobial solutions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.