Evidence map›Paper›PMID 42268958›Full record

ArticleScience advances2026

Lymph node microenvironment remodeling unlocks local antibody-mediated B cell depletion.

Zacarias Garcia, Margot Bardou, Anne Loap, Lea C Feldmann, Ophélie Godon, Marion V Guerin, Fabrice Lemaître, Lynn E Macdonald, Pierre Bruhns, Nicolas Serafini and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zacarias GarciaDynamics of Immune Responses Unit, Institut Pasteur, Université Paris Cité, INSERM U1223, Paris, France.ORCID 0000-0003-0774-809X
Margot BardouDynamics of Immune Responses Unit, Institut Pasteur, Université Paris Cité, INSERM U1223, Paris, France.ORCID 0009-0006-1924-8323
Anne LoapDynamics of Immune Responses Unit, Institut Pasteur, Université Paris Cité, INSERM U1223, Paris, France.
Lea C FeldmannDynamics of Immune Responses Unit, Institut Pasteur, Université Paris Cité, INSERM U1223, Paris, France.ORCID 0009-0002-3307-181X
Ophélie GodonInstitut Pasteur, Université Paris Cité, INSERM UMR1222, Antibodies in Therapy and Pathology, Paris, France.ORCID 0000-0003-1511-3764
Marion V GuerinDynamics of Immune Responses Unit, Institut Pasteur, Université Paris Cité, INSERM U1223, Paris, France.ORCID 0000-0003-2159-8518
Fabrice LemaîtreDynamics of Immune Responses Unit, Institut Pasteur, Université Paris Cité, INSERM U1223, Paris, France.ORCID 0000-0003-2287-6129
Lynn E MacdonaldRegeneron Pharmaceuticals, Tarrytown, NY, USA.ORCID 0000-0002-2547-4523
Pierre BruhnsInstitut Pasteur, Université Paris Cité, INSERM UMR1222, Antibodies in Therapy and Pathology, Paris, France.ORCID 0000-0002-4709-8936
Nicolas SerafiniInnate Immunity Unit, Institut Pasteur, Université Paris Cité, INSERM U1223, Paris, France.ORCID 0000-0002-7440-4353
Philippe BoussoDynamics of Immune Responses Unit, Institut Pasteur, Université Paris Cité, INSERM U1223, Paris, France.ORCID 0000-0002-6362-561X
Capucine L GrandjeanDynamics of Immune Responses Unit, Institut Pasteur, Université Paris Cité, INSERM U1223, Paris, France.ORCID 0000-0002-2901-7186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymph nodes (LNs) can act as reservoirs in CD20

Indexed as

Antibodies, MonoclonalB-LymphocytesCellular MicroenvironmentLymph NodesLymphocyte DepletionAnimalsAntigens, CD20HumansMiceAntibodies, MonoclonalAntigens, CD20

Identifiers

PMID42268958
PMCPMC13251840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.