Evidence map›Paper›PMID 42268884›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Ultrarapid MC1R protein and associated plumage color evolution in the domestic chicken.

Cheng Ma, Aenne-Dorothea Liebing, Gunnar Kleinau, Antje Kamprad, Louisa Calabrese, Michal Szczepek, Zheng Li, Mårten Larsson, Patrick Scheerer, Claudia Stäubert and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cheng Ma *Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala SE-751 23, Sweden.ORCID 0000-0002-9289-9791
Aenne-Dorothea Liebing *Rudolf Schönheimer Institute of Biochemistry, Faculty of Medicine, Leipzig University, Leipzig 04103, Germany.ORCID 0009-0003-2882-4386
Gunnar Kleinau *Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Structural Biology of Cellular Signaling, Berlin D-10117, Germany.ORCID 0000-0003-2131-671X
Antje KampradCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Structural Biology of Cellular Signaling, Berlin D-10117, Germany.ORCID 0000-0002-7488-1547
Louisa CalabreseCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Structural Biology of Cellular Signaling, Berlin D-10117, Germany.
Michal SzczepekCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Structural Biology of Cellular Signaling, Berlin D-10117, Germany.
Zheng LiDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala SE-751 23, Sweden.
Mårten LarssonDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala SE-751 23, Sweden.ORCID 0000-0002-7855-9539
Patrick ScheererCharité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Institute of Medical Physics and Biophysics, Group Structural Biology of Cellular Signaling, Berlin D-10117, Germany.ORCID 0000-0001-5028-2075
Claudia StäubertRudolf Schönheimer Institute of Biochemistry, Faculty of Medicine, Leipzig University, Leipzig 04103, Germany.ORCID 0000-0003-0721-8507
Leif AnderssonDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala SE-751 23, Sweden.ORCID 0000-0002-4085-6968

Funding

Deutsche Forschungsgemeinschaft (DFG) 407707190Deutsche Forschungsgemeinschaft (DFG) 421152132Erik Philip-Sorensen's Foundation for the Promotion of Genetic and Humanistic Scientific Research G2024-033Germany's Excellence Strategy-EXC 2008/1 (UniSysCat) 390540038Knut och Alice Wallenbergs Stiftelse (kawforskning) KAW 2023.0160Vetenskapsrådet (VR) VR 2017-02907
6 · The paper itself

Abstract

The domestic chicken exhibits extraordinarily high plumage diversity in sharp contrast to the uniform plumage phenotype in its wild ancestor, the red junglefowl. The

Indexed as

ChickensEvolution, MolecularFeathersPigmentationReceptor, Melanocortin, Type 1AllelesAnimalsMutation, MissensePhenotypeReceptor, Melanocortin, Type 1evolutiongene conversionintraexonic recombinationMC1Rplumage coloration

Identifiers

PMID42268884
PMCPMC13273276

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.