Evidence map›Paper›PMID 42268569›Full record

ArticleRadiological physics and technology2026

Clinical edge-case stress testing of two Asia-developed AI auto-contouring systems using prostate radiotherapy planning CT images.

Yuya Nagake, Keisuke Yasui, Ayami Sugiyama, Yasunori Saito, Hidetoshi Shimizu, Haruka Uezono, Naoki Hayashi

Abstract read
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Article in Radiological physics and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuya NagakeDepartment of Radiology, Fujita Health University Hospital, Aichi, 470-1192, Toyoake, Japan.
Keisuke YasuiDivision of Medical Physics, School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan. k-yasui@fujita-hu.ac.jp.ORCID http://orcid.org/0000-0002-5581-463X
Ayami SugiyamaGraduate School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Yasunori SaitoDepartment of Radiology, Fujita Health University Hospital, Aichi, 470-1192, Toyoake, Japan.
Hidetoshi ShimizuDivision of Medical Physics, School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Haruka UezonoDepartment of Radiation Oncology, School of Medicine, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.
Naoki HayashiDivision of Medical Physics, School of Medical Sciences, Fujita Health University, 1-98, Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To compare the geometric accuracy of two Asia‑developed AI auto‑contouring systems (RatoGuide and OncoStudio) for prostate radiotherapy planning CT, including performance in clinical edge cases. Planning CT data from 45 patients were stratified into four groups (Normal, Spacer, Seed/Spacer, GM/Spacer). Manual contours of prostate, rectum, bladder, seminal vesicles, and femoral heads served as reference. Segmentation accuracy was assessed using DSC and 95% Hausdorff distance; Wilcoxon signed‑rank and Mann-Whitney U tests were applied, with edge‑case analyses treated as exploratory. Median DSC exceeded 0.7 for all structures. RatoGuide performed better for the rectum, whereas OncoStudio performed better for the bladder, seminal vesicles, and femoral heads. Outliers were concentrated in combined implant/spacer groups. Both tools showed generally favorable geometric agreement, with structure‑dependent advantages and edge‑case outliers that warrant workflow‑aware quality assurance and future dosimetric validation.

Indexed as

Artificial IntelligenceImage Processing, Computer-AssistedProstatic NeoplasmsRadiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedAsiaAutomationHumansMaleAI-based auto-segmentationClinical edge casesPopulation-specific AIProstate radiotherapy

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.