Evidence map›Paper›PMID 42268474›Full record

ArticleNeurosurgical review2026

Spontaneous resorption of disc herniations in adjacent segment after endoscopic spine surgery: Cohort study.

Shunmin Wang, Kaiqiang Sun, Jincui Li, Yu Chen, Jiangang Shi

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Article in Neurosurgical review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Shunmin Wang *Department of Orthopedic Surgery, Changzheng Hospital, Navy Medical University, No.415 Fengyang Road, Shanghai, PR, 200003, China.ORCID http://orcid.org/0000-0003-2994-004X
Kaiqiang Sun *Department of Orthopedics, Naval Medical Center of PLA, Shanghai, 200052, P. R. China.
Jincui Li *Department of Orthopedic Surgery, Changzheng Hospital, Navy Medical University, No.415 Fengyang Road, Shanghai, PR, 200003, China.
Yu ChenDepartment of Orthopedic Surgery, Changzheng Hospital, Navy Medical University, No.415 Fengyang Road, Shanghai, PR, 200003, China. chenspine@126.com.
Jiangang ShiDepartment of Orthopedic Surgery, Changzheng Hospital, Navy Medical University, No.415 Fengyang Road, Shanghai, PR, 200003, China. changzhengspine@126.com.

Funding

The study is supported by the National Natural Science Foundation of China, Grant/Award Numbers: No. 81271828, No. 81702141 The study is supported by the National Natural Science Foundation of China, Grant/Award Numbers: No. 81271828, No. 81702141
6 · The paper itself

Abstract

backgroundAlthough spontaneous resorption of lumbar disc herniation (LDH) has been documented in the literature, its occurrence specifically in adjacent segments following endoscopic spine surgery remains unreported. This study aimed to investigate whether spontaneous resorption occurs in adjacent segments after endoscopic discectomy and to evaluate the associated clinical and radiological outcomes.

methodsA cohort of 91 patients diagnosed with single-segment LDH who underwent endoscopic surgery between 2020 and 2022 was included. Patients were classified into a Herniated group (n = 46) and a Bulging group (n = 45) based on preoperative MRI findings. Clinical outcomes were assessed using the Japanese Orthopedic Association (JOA) score and Visual Analog Scale (VAS). Radiological parameters, including disc height, protrusion volume, lumbar lordosis (Cobb angle), and paraspinal muscle morphology, were measured preoperatively and at final follow-up. Logistic regression was performed to identify predictors of resorption.

resultsBoth groups showed significant improvements in JOA and VAS scores postoperatively (P < 0.05). At final follow-up, reductions in disc height, lumbar curvature, protrusion volume, and protrusion ratio were observed in adjacent segments. Logistic regression analysis identified age (OR = 1.290, p = 0.009), preoperative protrusion volume (OR = 4.511, p = 0.014), and preoperative lumbar lordosis (OR = 0.481, p = 0.015) as independent predictors of spontaneous resorption.

conclusionsSpontaneous resorption of adjacent-segment LDH can occur after endoscopic surgery, particularly in younger patients with smaller protrusions and relatively preserved spinal alignment. These findings support a conservative, expectant management approach for asymptomatic or minimally symptomatic adjacent-segment protrusions, potentially reducing unnecessary surgical intervention. LEVEL OF EVIDENCE: III.

Indexed as

EndoscopyIntervertebral Disc DisplacementLumbar VertebraePostoperative ComplicationsAdultCohort StudiesDiskectomyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedTreatment OutcomeAdjacent segment degenerationEndoscopic spine surgeryIntervertebral disc disease

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.