ArticleMolecular biology reports2026
Antibacterial activity of selected plant essential oils against carbapenemase-producing multidrug-resistant bacteria.
Article in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfections caused by carbapenemase-producing multidrug-resistant (MDR) bacteria represent a major global health challenge, highlighting the urgent need for alternative antimicrobial agents.
methodsIn this study, MDR isolates of Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa were obtained from the microbial bank of Ahvaz Jundishapur University of Medical Sciences, Iran. The presence of carbapenemase genes (blaKPC, blaIMP, blaNDM, blaVIM-1, and blaOXA-48) was determined by polymerase chain reaction (PCR) in Gram-negative isolates. Essential oils (Eos) of Zataria multiflora, Mentha pulegium, Cinnamomum verum, and Zingiber officinale were extracted by hydrodistillation. Antibacterial activity was evaluated using the agar disc diffusion method and a modified disc-based concentration gradient approach to estimate minimum inhibitory concentrations (MICs).
resultsThe K. pneumoniae isolate harbored blaKPC and blaOXA-48, while P. aeruginosa carried blaIMP and blaNDM. No carbapenemase genes were detected in S. aureus. Among the tested EOs, Z. multiflora exhibited the strongest antibacterial activity, with inhibition zones up to 40 mm. C. verum demonstrated notable activity, particularly against K. pneumoniae (MIC: 1.56 mg/mL). M. pulegium showed moderate activity, whereas Z. officinale displayed no detectable antibacterial effect under the tested conditions. P. aeruginosa demonstrated comparatively higher resistance to all EOs.
conclusionSelected plant essential oils, particularly Z. multiflora and C. verum, demonstrated promising in vitro antibacterial activity against carbapenemase-producing MDR bacteria. Further investigations, including in vivo studies and chemical characterization of the oils, are warranted.
Indexed as
Identifiers
42268473What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.