ArticleMolecular biology reports2026
Hypoxia-reoxygenation cycle leads to context dependent phenotypic effects in breast cancer cell lines.
Article in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Correspondence: Beyond phenotypic observations: Elucidating the molecular drivers of hypoxia-reoxygenation-induced aggressiveness in breast cancer.Molecular biology reports · 2026Article
- Correspondence: Beyond phenotypic observations: elucidating the molecular drivers of hypoxia-reoxygenation-induced aggressiveness in breast cancer.Molecular biology reports · 2026Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypoxia is a common feature of solid tumors and is associated with cancer progression. We investigated the effect of hypoxia followed by reoxygenation on the phenotypic behavior of two breast cancer cell lines, MCF-7 and MDA-MB-231. METHODS AND
resultsMCF-7 and MDA-MB-231 cells were exposed to controlled hypoxia (1% O
conclusionThese findings suggest that hypoxia followed by reoxygenation results in transient alterations in multiple phenotypic traits, especially in less aggressive breast cancer cells, highlighting the need for strategies to mitigate hypoxia-driven tumour progression.
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Registered trials
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