Evidence map›Paper›PMID 42268311›Full record

ArticleMedical molecular morphology2026

G protein-coupled receptor 56-mediated lung metastasis mechanisms in osteosarcoma LM8 cells.

Nobuyoshi Suzuki, Erika Hayakawa, Hiroshi Nishiura, Wenting Chen, Mai Imasaka, Michihiko Sugimoto, Toshiya Tachibana, Masaki Ohmuraya

Abstract read
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In one paragraph

Article in Medical molecular morphology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nobuyoshi Suzuki *Department of Genetics, School of Medicine, Hyogo Medical University, 1-1, Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan.
Erika Hayakawa *Department of Genetics, School of Medicine, Hyogo Medical University, 1-1, Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan.
Hiroshi NishiuraDepartment of Genetics, School of Medicine, Hyogo Medical University, 1-1, Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan. hi-nishiura@hyo-med.ac.jp.ORCID http://orcid.org/0000-0002-5741-0276
Wenting ChenDepartment of Genetics, School of Medicine, Hyogo Medical University, 1-1, Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan.
Mai ImasakaDepartment of Genetics, School of Medicine, Hyogo Medical University, 1-1, Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan.
Michihiko SugimotoDepartment of Genetics, School of Medicine, Hyogo Medical University, 1-1, Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan.
Toshiya TachibanaDepartment of Orthopedic Surgery, School of Medicine, Hyogo Medical University, 1-1, Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan.
Masaki OhmurayaDepartment of Genetics, School of Medicine, Hyogo Medical University, 1-1, Mukogawa-Cho, Nishinomiya, Hyogo, 663-8501, Japan.

Funding

Hyogo College of Medicine Program 2025
6 · The paper itself

Abstract

Osteosarcoma has a poor prognosis and frequently metastasizes to the lungs. This study examined the role of transglutaminase 2 (TGM2), a ligand for adhesion G protein-coupled receptor 56 (GPR56), in lung metastasis of LM8 mouse osteosarcoma cells. Gβγ‑dependent ERK signaling mediated by GPR56 and the adhesion of GPR56-expressing LM8

Indexed as

AdhesionERK signalingGPR56LM8MetastasisTransglutaminase 2

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.