Evidence map›Paper›PMID 42268296›Full record

ReviewChinese medical journal2026

Advances in vascularized organoids.

Lanlin Shen, Jinhu Ma, Xiao Wei, Gang Shi, Hongxin Deng

Abstract readReview
In one paragraph

Review in Chinese medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lanlin ShenDepartment of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Jinhu Ma
Xiao Wei
Gang Shi
Hongxin Deng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractThe development of organoid technology has led to notable advances in regenerative medicine, disease modeling, and drug screening. However, given the pivotal role of vascular systems in growth maintenance and nutrient delivery, the lack of functional vascular networks within organoids limits the scalability and physiological functionality of these organoids. Efforts to explore strategies for organoid vascularization, such as co-culture, transcription factor induction, microfluidic technology, and the application of biomaterial scaffolds, are underway. These methods have shown distinct advantages across different types of organoids, partially addressing vascularization challenges. However, issues such as limited vascular network integration and insufficient functional maturity remain unresolved. Future efforts should prioritize the development of multi-tiered vascular networks, the application of smart biomaterials, and the creation of personalized vascularized organoids. This review summarizes the advances in this field and explores the potential translation of vascularized organoids into clinical practice, offering recommendations for further research.

Indexed as

OrganoidsAngiogenesisAnimalsCoculture TechniquesHumansTissue Engineering3D bioprintingCo-cultureMicrofluidic technologyVascularized organoids

Identifiers

PMID42268296
PMCPMC13485845

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.