Evidence map›Paper›PMID 42268249›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2026

Context-Dependent Effects of Apolipoprotein A2 on Lipid Metabolism and Atherogenesis.

Evangelia Zvintzou, Ioana Madalina Fenyo, Radu Ionita, Georgia Kakafoni, Madalina Dumitrescu, Maria Alemi, Bianca Sanziana Daraban, Konstantinos Marinos, Anca Violeta Gafencu, Kyriakos E Kypreos

Abstract read
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In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Evangelia ZvintzouPharmacology Laboratory Department of Medicine, University of Patras, Rio Achaias, Greece.
Ioana Madalina FenyoGene Regulation and Molecular Therapies Laboratory, Institute of Cellular Biology and Pathology, "Nicolae Simionescu" of the Romanian Academy, Bucharest, Romania.
Radu IonitaGene Regulation and Molecular Therapies Laboratory, Institute of Cellular Biology and Pathology, "Nicolae Simionescu" of the Romanian Academy, Bucharest, Romania.
Georgia KakafoniPharmacology Laboratory Department of Medicine, University of Patras, Rio Achaias, Greece.
Madalina DumitrescuGene Regulation and Molecular Therapies Laboratory, Institute of Cellular Biology and Pathology, "Nicolae Simionescu" of the Romanian Academy, Bucharest, Romania.
Maria AlemiPharmacology Laboratory Department of Medicine, University of Patras, Rio Achaias, Greece.
Bianca Sanziana DarabanGene Regulation and Molecular Therapies Laboratory, Institute of Cellular Biology and Pathology, "Nicolae Simionescu" of the Romanian Academy, Bucharest, Romania.
Konstantinos MarinosPharmacology Laboratory Department of Medicine, University of Patras, Rio Achaias, Greece.
Anca Violeta GafencuGene Regulation and Molecular Therapies Laboratory, Institute of Cellular Biology and Pathology, "Nicolae Simionescu" of the Romanian Academy, Bucharest, Romania.
Kyriakos E KypreosPharmacology Laboratory Department of Medicine, University of Patras, Rio Achaias, Greece.ORCID https://orcid.org/0000-0001-6784-2710

Funding

Academia Româna (Romanian Academy) GAR2023/82Academia Româna (Romanian Academy) GAR2023/83Andreas Mentzelopoulos Foundation 2025COST action CA21153Ministry of Education and Research, Romania (MINISTERUL EDUCAȚIEI ȘI CERCET ĂRII) PNRR/2022/C9/MCID/I8
6 · The paper itself

Abstract

Apolipoprotein A2 (APOA2) is a component of several plasma lipoproteins, yet its physiological and pathological functions remain unclear. Conflicting data regarding its effects on plasma lipid levels and cardiovascular risk indicate that APOA2 activity may be context dependent. Here, we employed adenovirus-mediated gene transfer of human APOA2 into male C57BL/6, ldlr

Indexed as

Apolipoprotein A-IIAtherosclerosisLipid MetabolismAnimalsApolipoproteins ECholesterolHumansMaleMiceMice, Inbred C57BLMice, KnockoutReceptors, LDLTriglyceridesApolipoprotein A-IIApolipoproteins ECholesterolReceptors, LDLTriglyceridesapolipoprotein A2apolipoprotein Bapolipoprotein Eatherosclerosisdyslipidemialow density lipoprotein receptor

Identifiers

PMID42268249
PMCPMC13251745

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.