Evidence map›Paper›PMID 42267923›Full record

ArticleInfection and immunity2026

Contributions of conserved and species-specific CagX (VirB9) domains to the assembly and function of the

Chiamaka D Okoye, Arwen E Frick-Cheng, Wilhelm Salmen, Sirena C Tran, W Hayes McDonald, John T Loh, Mark S McClain, D Borden Lacy, Melanie D Ohi, Timothy L Cover

Abstract read
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chiamaka D OkoyeDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-6366-0570
Arwen E Frick-ChengLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-7202-4701
Wilhelm SalmenLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.
Sirena C TranDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
W Hayes McDonaldMass Spectrometry Research Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
John T LohDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0001-6497-7652
Mark S McClainDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0002-9857-4883
D Borden LacyDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Melanie D OhiLife Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-1750-4793
Timothy L CoverDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0001-8503-002X

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MARY Kay WASHINGTON · 2002 to 2026
$29.9M
Role of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 2009 to 2026
$27.5M
Structure-function analysis of H. pylori VacAR01AI039657 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 1996 to 2026
$8.3M
Type IV Protein Secretion in Helicobacter pyloriR01AI118932 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COVER, TIMOTHY L, OHI, MELANIE DIANE · 2016 to 2025
$6.7M
Compute Cluster for in vitro and in situ Analysis of Molecular MachinesS10OD030275 · OD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OHI, MELANIE DIANE · 2021 to 2021
$600k
Structural Studies of Helicobacter Pyloris Cag Type IV Secretion SystemF32AI186525 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Wilhelm Salmen · 2025 to 2026
$164k
BLRD VA I01 BX004447NCI NIH HHS P01 CA116087NCI NIH HHS P30 CA068485NIAID NIH HHS F32 AI186525NIAID NIH HHS R01 AI039657NIAID NIH HHS R01 AI118932NIDDK NIH HHS P30 DK058404NIH HHS AI118932, AI039657NIH HHS AI186525NIH HHS CA116087NIH HHS S10 OD030275NIH HHS S10OD030275U.S. Department of Veterans Affairs 5I01BX004447
6 · The paper itself

Abstract

The

Indexed as

Bacterial ProteinsHelicobacter pyloriType IV Secretion SystemsAntigens, BacterialProtein DomainsAntigens, BacterialBacterial ProteinsType IV Secretion Systemsbacterial protein secretionbacterial secretion systemscrosslinking mass spectrometryHelicobacter pyloriproteomics

Identifiers

PMID42267923
PMCPMC13417560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.