Observational studyCritical care explorations2026
Divergence Between Net Fluid and Weight-Based Evaluation in Calculating Cumulative Fluid Balance.
Observational study in Critical care explorations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Differential associations of early fluid accumulation with acute kidney injury and mortality in critically ill children: a prospective cohort study with mediation and propensity-score analyses.Pediatric nephrology (Berlin, Germany) · 2026Article
- Fluid balance during PICU stay in children after cardiac surgery with cardiopulmonary bypass.European journal of pediatrics · 2026Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlthough efforts have been made to standardize fluid balance calculations in the ICU, there is a limited understanding of how different calculation methods relate to one another across an ICU admission. We quantified the agreement between the cumulative fluid balance calculated from fluid intake and output (CFBf) and cumulative fluid balance calculated from serial weights (CFBw) in critically ill children during the first week of ICU admission.
designRetrospective, multicenter, federated observational study.
settingFour pediatric medical-SICUs (PICU) and two pediatric cardiac ICUs (PCICU) from four tertiary care centers. PATIENTS: Analysis included 8,895 pediatric patients (younger than 19 yr) representing 12,388 ICU encounters from 2023 to 2024.
interventionsNone. MEASUREMENTS AND MAIN
resultsA patient's anchor weight was the weight closest to ICU admission. CFBf and CFBw were calculated at the time of new weight measurements. We assessed agreement between CFBf and CFBw using Bland-Altman analyses, stratified by ICU day and patient subgroups (neonates, early anchor weights [weight on ICU day 0], and encounters with unmeasured urine occurrences). Across all units and subgroups, CFBf exceeded CFBw (mean difference: all patients = 4.7 %CFB, early anchor weight = 4.7 %CFB, neonates = 5.9 %CFB). The mean difference increased significantly over time (days 0-3: 2.7% vs. days 4-7: 8.1%, p < 0.05), with greater divergence in neonates and those with early anchor weights.
conclusionsCFBf consistently exceeded CFBw across all subgroups, with a greater divergence on ICU days 4-7. Clinicians should understand these differences, prioritizing early and frequent patient weights throughout ICU admission. Future studies should assess each method's association with patient outcomes to identify the most clinically informative CFB method.
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