ReviewmSphere2026
The cutaneous microbiome: microbial remodeling of the skin lipid landscape.
Review in mSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects.iMeta · 2026Review
- Skin microbiome and cutaneous aging mechanisms and clinical implications.Frontiers in microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human skin microbiome exists within a lipid-rich environment that profoundly shapes microbial colonization, metabolism, and interactions with the host. Resident microbes not only consume host-derived lipids for energy but also transform them into bioactive compounds that influence microbial competition, immune responses, and skin barrier function. In turn, microbially generated lipids become part of the skin lipid landscape, including short-chain fatty acids and cell envelope lipids, and contribute to maintaining homeostasis or, in some cases, influence disease processes such as acne and atopic dermatitis. Despite increased recognition of their importance, the diversity, origins, and bioactivities of microbially derived lipids on skin remain underexplored. Here, we highlight recent advances in understanding how cutaneous microbes shape and are shaped by the skin lipid landscape, emphasizing the potential of microbial lipids as mediators of skin health, disease, and novel therapeutic strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.