Evidence map›Paper›PMID 42267809›Full record

ArticleApplied and environmental microbiology2026

Characterization and therapeutic potential of DepZ57, a stable depolymerase targeting hypervirulent K57

Sixiang Xu, Mengmeng Su, Xiaoyue Li, Pei Li, Xiangkuan Zheng, Huanxin Fang, Yilin Fang, Peifan Liu, Long Chen, Zihao Pan and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sixiang XuSanya Institute of Nanjing Agricultural University, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing, China.ORCID 0009-0005-7063-7597
Mengmeng SuSanya Institute of Nanjing Agricultural University, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing, China.
Xiaoyue LiSanya Institute of Nanjing Agricultural University, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing, China.
Pei LiCollege of Life Sciences and Food Engineering, Hebei University of Engineering, Handan, China.
Xiangkuan ZhengSanya Institute of Nanjing Agricultural University, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing, China.
Huanxin FangSanya Institute of Nanjing Agricultural University, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing, China.ORCID 0000-0002-6651-4595
Yilin FangSanya Institute of Nanjing Agricultural University, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing, China.
Peifan LiuSanya Institute of Nanjing Agricultural University, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing, China.
Long ChenDepartment of Clinical Laboratory, Zhangjiagang Hospital Affiliated to Soochow University, Zhangjiagang, China.
Zihao PanSanya Institute of Nanjing Agricultural University, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing, China.
Zhongming TanNHC Key Laboratory of Enteric Pathogenic Microbiology, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
Hong DuDepartment of Clinical Laboratory, the Second Affiliated Hospital of Soochow University, Suzhou, China.ORCID 0000-0002-2973-1523
Wei ZhangSanya Institute of Nanjing Agricultural University, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing, China.ORCID 0000-0002-3575-6225

Funding

Key R&D Program of Ningxia Hui Autonomous Region 2025BBF02009the Ding'an County Science and Technology Plan Project 202411002
6 · The paper itself

Abstract

IMPORTANCE: The emergence of multidrug-resistant and hypervirulent

Indexed as

BacteriophagesGlycoside HydrolasesKlebsiella InfectionsKlebsiella pneumoniaeViral ProteinsAnimalsBacterial ProteinsFemaleMiceMice, Inbred BALB CPhagocytosisBacterial Proteinscapsular-polysaccharide galactohydrolaseGlycoside HydrolasesViral ProteinsbacteriophagedepolymeraseIn vivo efficacyK57 serotypeKlebsiella pneumoniaestability assessment

Identifiers

PMID42267809
PMCPMC13390486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.