Evidence map›Paper›PMID 42267772›Full record

ArticleProceedings (Baylor University. Medical Center)2026

National and state-level trends in digestive diseases in the United States, 1990 to 2021.

Omar Al Ta'ani, Saqr Alsakarneh, Yazan Al-Ajlouni, Ahmed Gabr, Chloe Lahoud, Pojsakorn Danpanichkul, Dushyant Dahiya Singh, Razan Aburumman, Yahya Alhalalmeh, Basile Njei

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In one paragraph

Article in Proceedings (Baylor University. Medical Center), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Understanding the gap and addressing disparities in US digestive health.Proceedings (Baylor University. Medical Center) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Omar Al Ta'aniDepartment of Internal Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.
Saqr AlsakarnehDepartment of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
Yazan Al-AjlouniDepartment of Physical Medicine and Rehabilitation, Montefiore Medical Center, Bronx, New York, USA.ORCID 0000-0002-1718-4964
Ahmed GabrDepartment of Medicine, New York Medical College, New York City, New York, USA.
Chloe LahoudDepartment of Internal Medicine, Zucker School of Medicine, Staten Island, New York, USA.
Pojsakorn DanpanichkulDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Dushyant Dahiya SinghDepartment of Gastroenterology and Hepatology, University of Kansas, Kansas City, Kansas, USA.
Razan AburummanDepartment of Internal Medicine, Henry Ford Hospital, Detroit, Michigan, USA.
Yahya AlhalalmehNew York Medical College-Saint Michael's Medical Center, Newark, New Jersey, USA.
Basile NjeiYale International Medicine Program, Yale University, New Haven, Connecticut, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDigestive diseases are a major cause of morbidity and mortality in the United States, placing a substantial burden on healthcare.

methodsData from the 2021 Global Burden of Disease study were analyzed for all 50 US states and the District of Columbia. Temporal trends were quantified using estimated annual percentage changes, and correlations with the Socio-Demographic Index were assessed using Pearson's correlation.

resultsFrom 1990 to 2021, total incident digestive diseases cases rose from 20.1 to 26.2 million, a 30.5% increase, while age-standardized incidence rates declined by 9.8%. Age-standardized disability-adjusted life year (DALY) rates decreased by 7.7%, and death rates fell by 5.9%. Most digestive diseases showed declining DALY rates; however, cirrhosis and other chronic liver diseases increased by 4.5% and remained the highest contributor to DALYs, with a 9% rise in mortality. Inflammatory bowel disease also increased, with DALYs rising by 12% in males and 23% in females; mortality rose by 64% in females versus 44% in males.

conclusionThese findings reveal both progress and persistent disparities, with higher burdens among women and states with a lower Socio-Demographic Index. Targeted interventions and resource allocation are warranted to address these inequities.

Indexed as

Digestive System DiseasesAdultDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseHumansIncidenceMaleMiddle AgedUnited StatesBurden of diseasedigestive diseasesincidence trendspublic healthsocioeconomic disparitiesUnited States

Identifiers

PMID42267772
PMCPMC13523998

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.