Evidence map›Paper›PMID 42267382›Full record

ArticleERJ open research2026

Robotic

Aniek R C Bruinen, Roel L J Verhoeven, Gerjon Hannink, Erik H F M van der Heijden

Abstract read
In one paragraph

Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aniek R C BruinenDepartment of Pulmonary Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0009-0009-9310-5816
Roel L J VerhoevenDepartment of Pulmonary Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-7892-4700
Gerjon HanninkMedical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.
Erik H F M van der HeijdenDepartment of Pulmonary Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-3596-518X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Small peripheral pulmonary lesions are nowadays preferably diagnosed by navigation bronchoscopy, yet reported diagnostic yields vary across different techniques. Shape-sensing robotic-assisted bronchoscopy (ssRAB), now also available in Europe, combines real-time shape sensing with an actively steerable catheter, potentially improving diagnostic yield. We aimed to compare ssRAB combined with cone-beam computed tomography (CBCT) imaging (ssRAB+CBCT) against our current standard, CBCT-based navigation bronchoscopy (CBCT-NB) alone. Methods: We conducted a single-centre, propensity score-matched analysis comparing patients undergoing ssRAB+CBCT with patients undergoing CBCT-NB for the diagnosis of small peripheral pulmonary lesions. Matching was performed on known lesion characteristics influencing yield. Primary outcome was strict diagnostic yield. Secondary outcomes included diagnostic accuracy at follow-up, safety and procedure-related metrics. Results: A total of 131 patients with 183 biopsied lesions were included in the ssRAB+CBCT arm. Median lesion size was 12 mm (interquartile range 8-18 mm). Propensity score matching with lesions from our reference CBCT-NB cohort was successful in 150 out of 183 lesions. The diagnostic yield at the lesion level was 73% for the ssRAB+CBCT arm and 70% for the CBCT-NB arm; the mean difference of 3.3% (95% CI -6.9-13.5%) was not statistically significant (p=0.521). The diagnostic yield at the patient level for the ssRAB+CBCT arm was 82%. Conclusion: ssRAB+CBCT has a diagnostic yield similar to that of our highly optimised CBCT-NB programme, and was below the study's powering assumption of a 15% increase in diagnostic yield. There was a suggestion of benefit in small nodules with a negative bronchus sign. The unique features of ssRAB mean that it holds promise, but larger studies are warranted to clarify its position and optimal case selection, compared with other navigation bronchoscopy technologies, its clinical impact and its cost-effectiveness.

Identifiers

PMID42267382
PMCPMC13244196

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.