ArticleRevista brasileira de ortopedia2026
Neuropathic Pain in Patients Undergoing Primary Total Knee Arthroplasty: Preval ence and Risk Factors.
Article in Revista brasileira de ortopedia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to evaluate the prevalence and risk factors of neuropathic pain (NP) in patients undergoing primary total knee arthroplasty (TKA). Methods: The present prospective observational study included patients aged 18 years or older who were candidates for TKA, conducted between October 2023 and October 2024 at a university hospital. Data were collected from medical records and through the application of a questionnaire assessing socioeconomic variables, comorbidities, prior treatments, and the interview version of the Douleur Neuropathique in 4 questions (DN4i) questionnaire, a validated screening instrument for NP. Paired samples were analyzed using the Wilcoxon, Chi-squared of independence, and Fisher's exact tests, with a significance level set at Results: Of the 68 participants, 20 (29%) tested positive for NP. Among these, most were female (80%, Conclusion: There is a high prevalence of NP among patients undergoing TKA, particularly in females, and is associated with worse quality of life and greater pain intensity. Systematic screening using the DN4i questionnaire may improve diagnosis and support the development of individualized therapeutic strategies.
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