Evidence map›Paper›PMID 42267315›Full record

ArticleJAC-antimicrobial resistance2026

Andrew Bryan, Megan Shields-Pruiett, Heather Berger, Ferric C Fang, Kelsi Penewit, Adam Waalkes, Elizabeth A Holmes, Stephen J Salipante, Brian J Werth

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew BryanDepartment of Laboratory Medicine and Pathology, Mayo Clinic Arizona, Phoenix, USA.ORCID https://orcid.org/0000-0003-0764-8697
Megan Shields-PruiettLaboratory Services, Samaritan Health Services, Lebanon, OR, USA.
Heather BergerDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Ferric C FangDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0002-3243-110X
Kelsi PenewitDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0003-1454-6381
Adam WaalkesDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0002-5202-1108
Elizabeth A HolmesDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Stephen J SalipanteDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0001-8355-6992
Brian J WerthDepartment of Pharmacy, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0001-6751-4098

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss, Lucas R Hoffman · 2010 to 2026
$21.4M
Contribution of altered lipid metabolism to resistance to cell envelope-targeting antimicrobials in MRSAR01AI136979 · NIAID · UNIVERSITY OF WASHINGTON · PI Brian James Werth, Libin Xu · 2018 to 2026
$4.1M
NIAID NIH HHS R01 AI136979NIDDK NIH HHS P30 DK089507
6 · The paper itself

Abstract

Objectives: Carbapenem resistance is a growing public health crisis with regional variability in incidence. We characterized the susceptibility of carbapenem-resistant Gram-negative rods (CR-GNRs) from the Pacific Northwest to five reserve beta-lactam agents including cefiderocol and aztreonam-avibactam. Methods: A panel of 162 CR-GNRs from unique patients were tested against cefiderocol, aztreonam-avibactam, ceftazidime-avibactam, meropenem-vaborbactam and ceftolozane-tazobactam, with a subset of isolates derived from patients with bacteraemia ( Results: Among all isolates, the MIC Conclusions: Cefiderocol exhibited the greatest

Identifiers

PMID42267315
PMCPMC13245396

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.