Evidence map›Paper›PMID 42267165›Full record

ArticleFrontiers in psychiatry2026

Factors influencing the sensory profile in patients with autism spectrum disorder from 16 months to 14 years: results of an observational study.

Nadia Marani, Davide di Gennaro, Raffaele Garotti, Valeria Maffettone, Rosamaria Siracusano, Maria Pia Riccio, Simone Pisano, Carmela Bravaccio

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Nadia MaraniDepartment of Maternal and Child Health, Child and Adolescent Neuropsychiatry, AOU "Federico II", Naples, Italy.
Davide di GennaroResidency Program of Child and Adolescent Neuropsichiatry, Department of Medical and Translational Science, Federico II University, Naples, Italy.
Raffaele GarottiDepartment of Maternal and Child Health, Child and Adolescent Neuropsychiatry, AOU "Federico II", Naples, Italy.
Valeria MaffettoneDepartment of Psychology, University of Campania "Luigi Vanvitelli", Naples, Italy.
Rosamaria SiracusanoDepartment of Maternal and Child Health, Child and Adolescent Neuropsychiatry, AOU "Federico II", Naples, Italy.
Maria Pia RiccioDepartment of Maternal and Child Health, Child and Adolescent Neuropsychiatry, AOU "Federico II", Naples, Italy.
Simone PisanoDepartment of Medical and Translational Sciences, Child Neuropsychiatry, Federico II University, Naples, Italy.
Carmela BravaccioDepartment of Medical and Translational Sciences, Child Neuropsychiatry, Federico II University, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Sensory processing abnormalities represent a high-impact clinical feature in individuals with Autism Spectrum Disorder (ASD). Sensory alterations can be classified by modality and behavioral responses to stimuli. The literature presents conflicting results regarding the association between the sensory profile and other clinical elements. Therefore, this study aimed to characterize the clinical variables that influence sensory anomalies in subjects with ASD. Methods: This single-center retrospective observational study selected 159 subjects with a confirmed ASD diagnosis, aged 16 months to 14 years. Data collected included clinical assessments (developmental profile, intelligence quotient, adaptive profile and autistic symptom severity) and sensory evaluations using the Sensory Profile-2. A Bayesian cumulative logit model was implemented to assess the impact of clinical variables on sensory profiles. Results: The analysis identifies adaptive functioning as the most consistent predictor of sensory outcomes, where higher functioning correlates with a reduction in atypical patterns, particularly sensory sensitivity. Conversely, autism severity and sex generally showed no significant impact, though higher cognitive functioning was specifically linked to increased sensory avoiding behaviors. Furthermore, the Bayesian analysis revealed a modifying effect of age on the sensory profile, characterized by a non-monotonic trend clustered around two distinct age peaks. The preschool period is characterized by a predominance of sensory seeking behaviors and auditory processing challenges, whereas the 8-to-12-year developmental window marks a significant shift toward hypersensitivity and avoidant patterns, particularly within the visual and oral modalities. Discussion: Overall, the analysis revealed that the adaptive profile has a significant impact on the sensory profile, consistent with existing literature. Age emerged as a key modifying factor with a non-monotonic trajectory, contrasting with previous studies that typically highlight either improvement or stability over time. Study main limitations include its retrospective and non-longitudinal nature. Therefore, further prospective longitudinal studies are necessary to explore these dynamic associations between the sensory profile and other clinical variables over time.

Indexed as

adaptive functionageautism spectrum disordercognitive functionsensory profile

Identifiers

PMID42267165
PMCPMC13243405

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