Evidence map›Paper›PMID 42267093›Full record

ArticleSouthern African journal of infectious diseases2026

Factors associated with

Denasha L Reddy, Ziyaad Dangor, Lyle Murray, Jacob M Tsitsi, Jeremy S Nel, Trusha Nana, Jeannette Wadula, Rispah Chomba, Sinenhlanhla Ndzabandzaba, Vicky L Baillie and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Southern African journal of infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Denasha L ReddySouth African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-1199-021X
Ziyaad DangorSouth African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0003-4089-147X
Lyle MurrayDepartment of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-3577-284X
Jacob M TsitsiDepartment of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-1417-1324
Jeremy S NelDepartment of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0003-4115-894X
Trusha NanaDepartment of Clinical Microbiology and Infectious Diseases, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-0216-1575
Jeannette WadulaDepartment of Clinical Microbiology and Infectious Diseases, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-1083-6173
Rispah ChombaDepartment of Clinical Microbiology and Infectious Diseases, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0003-3147-6688
Sinenhlanhla NdzabandzabaDepartment of Clinical Microbiology and Infectious Diseases, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-3514-9695
Vicky L BaillieSouth African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0003-1327-9090
Courtney P OlwagenSouth African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0009-0007-3674-8415
Shabir A MadhiSouth African Medical Research Council Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-7629-0636

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is a paucity of data on gastrointestinal colonisation with Objectives: We investigated the risk factors for KPn gastrointestinal colonisation among a cohort of hospitalised adults without KPn-ID in South Africa, and described their clinical outcomes. Method: A cohort of hospitalised adults without KPn-ID was enrolled between 15 May 2023 to 14 May 2024 across three hospitals in Johannesburg, South Africa. Study participants had rectal swab cultures performed once, at enrolment, to determine the presence or absence of KPn gastrointestinal colonisation, and were followed up until in-hospital death or discharge. Results: Among the cohort of hospitalised adults without KPn-ID ( Conclusion: KPn gastrointestinal colonisation rates among hospitalised adults without KPn-ID were higher than that of high-income settings and also varied between study sites. Length of hospital admission prior to swabbing and pHAI were associated with KPn colonisation, suggesting that infection prevention control measures play a significant role in KPn colonisation. Contribution: Large prospective cohort studies and community surveillance studies are required in settings such as ours to further investigate KPn colonisation dynamics and explore preventive strategies against KPn-ID.

Indexed as

central venous cathetergastrointestinal colonisationinfection prevention and controlinvasive diseaseKlebsiella pneumoniaepresumed healthcare-associated infection

Identifiers

PMID42267093
PMCPMC13243837

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.