ArticleAnnals of thoracic surgery short reports2026
Preoperative Intestinal Preconditioning to Prevent Postoperative Vasoplegia After Tricuspid Valve Surgery.
Article in Annals of thoracic surgery short reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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14 authors.
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Abstract
Background: Right ventricular dysfunction may lead to intestinal bacterial translocation secondary to portal venous hypertension, thereby contributing to systemic inflammatory response syndrome and vasoplegia after tricuspid valve surgery. This study aimed to evaluate the impact of preoperative intestinal preconditioning (oral antibiotics and laxatives) on the occurrence of postoperative vasoplegia after tricuspid valve surgery. Methods: This retrospective single-center analysis included patients who underwent tricuspid valve surgery from 2017 to 2021. The outcomes of patients who received preoperative intestinal preconditioning were compared with the outcomes of patients who did not. Primary outcomes were in-hospital mortality and the occurrence of postoperative vasoplegia. Secondary outcomes were intensive care unit (ICU) and hospital length of stay (LOS). Results: Among 142 patients, 44 (30.9%) received preoperative preconditioning, whereas 98 (69.0%) did not. Baseline characteristics were similar between the groups. In-hospital mortality rates were comparable (6.8% vs 5.1%, with and without preconditioning, respectively; Conclusions: Preoperative intestinal preconditioning before tricuspid valve surgery may prevent postoperative vasoplegia. Lower vasoplegia rates are associated with reduced ICU and hospital LOSs and improved in-hospital mortality.
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