ArticleAmerican journal of cancer research2026
Curcumin induces ferroptosis in ovarian cancer cells through the Nrf2/GPX4 regulation axis.
Article in American journal of cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Targeting SLC7A11 with Chinese Medicine for Tumor Ferroptosis Induction: From Molecular Mechanisms to Novel Precision Therapeutic Strategies.Chinese journal of integrative medicine · 2026Review
- Plant Bioactive Constituents and Their Potential Benefits in HPV-Positive Oropharyngeal Squamous Cell Carcinoma-A Narrative Review.Current issues in molecular biology · 2026Review
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Authors and funding
10 authors.
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Abstract
Ovarian cancer (OC) frequently develops acquired resistance to traditional anti-tumor treatments, highlighting the urgent need for novel therapeutic strategies. This study investigated whether curcumin can induce ferroptosis in OC cells through the Nrf2/GPX4 regulation axis, and whether Nrf2 overexpression can confer resistance to curcumin in OC cells. SK-OV-3 and A2780 cells were treated with curcumin, and the effects on cell viability, migration, and invasion were evaluated using Cell Counting Kit-8 (CCK-8), wound healing, Transwell assay, and flow cytometry. Ferroptosis-associated changes were assessed by measuring intracellular Fe
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