ArticleNutrition research and practice2026
Vitamin D deficiency modifies the association between ambient PM
Article in Nutrition research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesMaintaining muscular power is essential for preventing sarcopenia and ensuring optimal physical performance. Although inadequate vitamin D levels and environmental pollutants are increasingly recognized as threats to musculoskeletal integrity, their synergistic impact has not been fully established. This study examined how the vitamin D status and atmospheric contaminants independently and collectively influence the prevalence of suspected sarcopenia, defined strictly as low handgrip strength. SUBJECTS/
methodsThis cross-sectional analysis included 20,304 individuals from the Health Examinees cohort using baseline data. Vitamin D insufficiency was categorized as circulating 25-hydroxyvitamin D [25(OH)D] concentrations below 20 ng/mL. Residential address-linked data were used to estimate the annual mean exposure to nitrogen dioxide (NO
resultsSuboptimal vitamin D levels were widespread in the cohort (65.0%) and strongly correlated with increased pollutant exposure. After accounting for all potential confounders, elevated PM
conclusionVitamin D deficiency and air pollution exposure are independently associated with possible sarcopenia. In particular, PM
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