Evidence map›Paper›PMID 42266645›Full record

ArticleCephalalgia reports2025

Telemedicine-based cognitive behavioral therapy (TENACITY) for Veterans with chronic migraine: A pilot randomized controlled trial protocol.

Teresa M Damush, Samantha M Calcatera, Olivia Datre, Lindsey Hayley, Charles Austin, Emily L Schlitz, Carin Lea Eubanks, Lynnie Harrison, Doyle Yuan, Stanley Taylor and 5 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cephalalgia reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04613362 (TENACITY), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04613362 nacompletednot on this map

TENACITY: TelemEdiciNe-bAsed Cognitive Therapy for Migraine

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2021 to 2023Enrolled80ConditionsMigraine HeadacheArmsTENACITY Telehealth Cognitive Behavioral Therapy for Migraine, Behavioral Usual Care
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Teresa M DamushVeterans Health Administration (VHA) Headache Centers of Excellence Research, Evaluation, Education, Engagement Centers of Headache (RE3ACH), West Haven, CT, USA.ORCID 0000-0002-6544-2577
Samantha M CalcateraVeterans Health Administration (VHA) Headache Centers of Excellence Research, Evaluation, Education, Engagement Centers of Headache (RE3ACH), West Haven, CT, USA.
Olivia DatreVeterans Health Administration (VHA) Headache Centers of Excellence Research, Evaluation, Education, Engagement Centers of Headache (RE3ACH), West Haven, CT, USA.
Lindsey HayleyVeterans Health Administration (VHA) Headache Centers of Excellence Research, Evaluation, Education, Engagement Centers of Headache (RE3ACH), West Haven, CT, USA.
Charles AustinCenter for Health Information and Communications, Veterans Health Indiana, Indianapolis VAMC, IN, USA.
Emily L SchlitzBirmingham VA Healthcare System, Birmingham, AL, USA.
Carin Lea EubanksBirmingham VA Healthcare System, Birmingham, AL, USA.
Lynnie HarrisonBirmingham VA Healthcare System, Birmingham, AL, USA.
Doyle YuanNorthern Texas Veterans Healthcare System, Dallas, TX, USA.
Stanley TaylorCenter for Health Information and Communications, Veterans Health Indiana, Indianapolis VAMC, IN, USA.
Mindy FlanaganCenter for Health Information and Communications, Veterans Health Indiana, Indianapolis VAMC, IN, USA.
John NeyVeterans Health Administration (VHA) Headache Centers of Excellence Research, Evaluation, Education, Engagement Centers of Headache (RE3ACH), West Haven, CT, USA.
Elizabeth K SengVeterans Health Administration (VHA) Headache Centers of Excellence Research, Evaluation, Education, Engagement Centers of Headache (RE3ACH), West Haven, CT, USA.ORCID 0000-0002-8938-4949
Jason J SicoVeterans Health Administration (VHA) Headache Centers of Excellence Research, Evaluation, Education, Engagement Centers of Headache (RE3ACH), West Haven, CT, USA.
Amy S GrinbergVeterans Health Administration (VHA) Headache Centers of Excellence Research, Evaluation, Education, Engagement Centers of Headache (RE3ACH), West Haven, CT, USA.ORCID 0000-0003-4141-9513

Funding

HSRD VA IK6 HX002715HSRD VA IK6 HX003907
6 · The paper itself

Abstract

Background: Behavioral interventions for people with headache (HA) diseases have demonstrated clinical efficacy. Despite strong empirical support and endorsement by professional practice organizations, behavioral interventions are not widely accessible to HA patients. Clinic-based behavioral treatments remain inaccessible to many. The objectives of this study are to conduct a pilot randomized controlled trial and to determine the feasibility of the implementation of a cognitive behavioral therapy protocol for HA (CBT-HA) delivered via telehealth (TENACITY) compared to enhanced HA usual treatment (EHUT). Methods/design: TENACITY is a single-blinded, randomized, controlled, pilot trial with a single intervention arm and an EHUT control arm analyzed as intention-to-treat. This multi-site study had a 31-day run-in/screening period to confirm chronic migraine and an approximately 12-week CBT-HA treatment period. Follow-up assessments were conducted at 3- and 6-month post-treatment initiation. Analysis plan: The primary outcome will be analyzed as the change in self-reported number of HA days from the 30-day baseline run-in period before treatment to the number of self-reported days at 3 months post-treatment using a generalized mixed effects model. Secondary outcomes at 3- and 6-month post-treatment will be analyzed in addition. Trial Registration: IRP 20-002, TENACITY: Telemedicine-based cognitive therapy for migraine NCT04613362.

Indexed as

cognitive behavioral therapyheadacheMigrainetelehealth

Identifiers

PMID42266645
PMCPMC13245590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.