ArticleFrontiers in nutrition2026
Low BMI increases the risk of metabolic acidosis in children with dehydration.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Metabolic acidosis (MA) is one of the key factors determining the need for inpatient care in children with dehydration. This study aimed to identify risk factors for the development of MA in otherwise healthy children presenting with dehydration. Methods: A total of 328 children (50.9% girls, aged 3 months to 15 years) without a history of relevant chronic disease and hospitalized with acute dehydration were analyzed retrospectively. Selected anamnestic, clinical, and anthropometric factors potentially associated with MA were evaluated. MA was defined as a blood pH < 7.36 and a serum bicarbonate (HCO₃ Results: Metabolic acidosis occurred in 117 children (35.6%, mean age 4.93 ± 2.14 years). In multivariate logistic regression analysis, MA was independently associated with a higher degree of dehydration ( Conclusion: Low BMI and absence of diarrhea were identified as additional risk factors, alongside dehydration severity, for the development of MA in children with acute dehydration.
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