Evidence map›Paper›PMID 42266581›Full record

ArticleFrontiers in neurology

Machine learning-based triage model for elderly traumatic brain injury patients in Chinese emergency department.

Yanya Lin, Chengda Lin, Jianhui Chen, Shijun Chen, Jianhuang Huang, Jianxiong Hu

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Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yanya LinDepartment of Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.
Chengda LinDepartment of Neurosurgery, Putian 95 Hospital of China RongTong Medical and Health Group, Putian, China.
Jianhui ChenDepartment of Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.
Shijun ChenDepartment of Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.
Jianhuang HuangDepartment of Neurosurgery, Affiliated Hospital of Putian University, Putian, China.
Jianxiong HuDepartment of Critical Care Medicine, Affiliated Hospital of Putian University, Putian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Elderly traumatic brain injury (TBI) patients pose triage challenges in emergency departments due to complex physiology and comorbidities. Traditional methods often miss high-risk cases, necessitating accurate models to optimize ICU allocation. Methods: We developed an XGBoost-based triage model using data from 413 elderly TBI patients (aged ≥60 years) at Putian University Affiliated Hospital (2015-2024). Features included symptoms, CT hematoma density, contusion severity, age, anticoagulant use, and GCS scores. The target was ICU triage disposition within 48 h of ED presentation. Data were split (80:20) into training and testing sets. Class imbalance was handled within the training process using SMOTE, and model performance was assessed with 5-fold cross-validation using AUC, recall, precision, F1 score, and MCC. Because this was a prediction study rather than a causal inference analysis, all model outputs were interpreted as prediction of historical ICU triage disposition rather than proof of true ICU need. Complete-case analysis was used for model development after exclusion of records with missing key variables. SHAP analysis was used to improve interpretability. Results: The XGBoost model achieved an AUC of 0.93, recall of 0.9288, precision of 0.9274, F1 score of 0.9249, and MCC of 0.7241, outperforming the comparator models. Symptoms, CT hematoma density, and contusion severity were key predictors. Decision curve analysis suggested a higher theoretical net benefit than the "treat all" and "treat none" strategies across a clinically relevant threshold range; however, this finding should not be interpreted as a direct estimate of reduced unnecessary ICU admissions without prospective outcome-based validation. Conclusion: The XGBoost model provides an interpretable tool for predicting ICU triage disposition in elderly TBI patients and may support, rather than replace, emergency physician decision-making. Because the endpoint was a single-center process-of-care surrogate, further prospective and multicenter validation against patient-centered outcomes, including mortality, neurological deterioration, neurosurgical intervention, and functional status, is required.

Indexed as

clinical decision supportelderlyemergency departmentmachine learningSHAPtraumatic brain injurytriage

Identifiers

PMID42266581
PMCPMC13243014

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.