Evidence map›Paper›PMID 42266563›Full record

ArticleACG case reports journal2026

Desquamating Esophagitis in the Era of Immune Checkpoint Inhibitors: A Rare Upper Gastrointestinal Manifestation.

Sanjeevani Tomar, Kegan Jessamy, Dennis Yang, Maham Hayat

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sanjeevani TomarDepartment of Gastroenterology and Hepatology, AdventHealth Orlando, Orlando, FL.
Kegan JessamyLake Gastroenterology Associates, Taveras, FL.
Dennis YangCenter of Interventional Endoscopy, AdventHealth Orlando, Orlando, FL.
Maham HayatCenter of Interventional Endoscopy, AdventHealth Orlando, Orlando, FL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Desquamating esophagitis is a rare sloughing disorder of the esophageal mucosa most commonly associated with medications, autoimmune disease, or mucosal injury. Immune checkpoint inhibitors rarely cause esophageal involvement. We report a case of a 65-year-old woman with metastatic cervical cancer who developed progressive dysphagia 3 months after initiation of pembrolizumab. Endoscopy revealed severe proximal stenosis associated with desquamating esophagitis. She required frequent dilations but demonstrated marked and durable resolution after systemic corticosteroid therapy. This case highlights desquamating esophagitis as an uncommon immune-related adverse event and emphasizes that timely immunosuppression can reverse refractory inflammatory stricture.

Indexed as

desquamating esophagitisdysphagiaesophageal strictureesophagitis dissecans superficialisimmune checkpoint inhibitorimmune-related adverse event

Identifiers

PMID42266563
PMCPMC13246046

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.