ArticleJournal of dental anesthesia and pain medicine2026
Evaluation of phytochemical components, cytotoxicity, and molecular docking of
Article in Journal of dental anesthesia and pain medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Background: Synthetic intraoral topical anesthetics, such as lignocaine and benzocaine can cause adverse effects in pediatric dentistry, creating a need for safer plant-based alternatives. Methods: Ethanolic extracts of Results: HPLC and GC-MS confirmed the presence of bioactive compounds, including pyrethrin and furanoeudesma-1,3-diene, and the functional groups were validated by FTIR. Cytotoxicity assays revealed high biocompatibility, with half-maximal Inhibitory Concentration (IC Conclusion: Phytochemical, cytotoxic, and molecular docking analyses confirmed the anesthetic potentials of
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