Evidence map›Paper›PMID 42266170›Full record

Trial reportActa obstetricia et gynecologica Scandinavica2026

Immediate placement of intrauterine device after second-trimester medical abortion-Secondary outcomes with one-year follow-up.

Sara Hogmark, Caroline Westermark, Niklas Envall, Kristina Gemzell-Danielsson, Helena Kopp Kallner

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Acta obstetricia et gynecologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03603145 (Immediate Versus Delayed Insertion of Intrauterine Contraception at the Time of Medical Abortion- An Open-label, Randomized, Multicenter Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03603145 phase3unknown statusnot on this map

Immediate Versus Delayed Insertion of Intrauterine Contraception at the Time of Medical Abortion- An Open-label, Randomized, Multicenter Study

TypeinterventionalSponsorKarolinska InstitutetRan2019 to 2024Enrolled720ConditionsContraceptive UsageArmsImmediate insertion
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sara HogmarkDepartment of Clinical Sciences Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-6061-3982
Caroline WestermarkDepartment of Clinical Sciences Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0009-0007-2718-1664
Niklas EnvallDepartment of Clinical Sciences Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-2813-7642
Kristina Gemzell-DanielssonDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-6516-1444
Helena Kopp KallnerDepartment of Clinical Sciences Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden.

Funding

Karolinska Institutet K 0138-2015Karolinska Institutet LS-2016-1376Karolinska Institutet LS 2018-1257Karolinska Institutet RS 2019-1054Svenska Läkaresällskapet SLS-692651
6 · The paper itself

Abstract

introductionIntrauterine devices (IUDs) effectively prevent unwanted pregnancies. Little is known about long-term outcomes of women choosing an IUD after second-trimester medical abortion. MATERIAL AND

methodsWe performed a 12-month follow-up of a multicenter randomized controlled trial comparing IUD placement within 48 h (intervention) with placement at 2-4 weeks (control) after medical abortion with 85 to 153 days' gestation. Secondary outcomes such as proportions of long-term IUD use, subsequent pregnancies and abortions, and participant satisfaction are presented (ClinicalTrials.gov NCT03603145).

resultsA total of 179 women were included. The 12-month follow-up rate was 71.1% (64/90) in the intervention group and 73.0% (65/89) in the control group. Fewer women in the intervention group were using an IUD after 12 months: 51.6% (33/64) vs. 69.2% (45/65, p = 0.04). The total expulsion rate over 12 months was 36.4% (24/66) in the intervention group compared to 3.1% (2/65) in the control group (p < 0.001), with only two IUDs being expelled between 6 and 12 months, both in the intervention group. The most common contraceptive method at 12 months was any hormonal IUD at 54.3% (70/129). Among IUD users at 12 months, the overall satisfaction with their contraceptive method was high, at 88.3% (68/77). In the intervention group, 26.2% (16/61) had at least one subsequent pregnancy within 12 months compared to 13.6% (9/66, p = 0.08) in the control group. We found no significant difference in the number of subsequent abortions; 13.1% (8/61) in the intervention group and 6.1% (4/66) in the control group reported at least one subsequent abortion (p = 0.23).

conclusionsImmediate IUD placement after second-trimester medical abortion did not lead to a higher proportion of IUD use at 12 months compared to delayed placement. Rather, immediate IUD placement was associated with a higher incidence of expulsion and lower use; however, no significant increase in subsequent pregnancies or abortions was observed. High satisfaction levels with IUD use were reported in both groups, but women with immediate placement were less likely to recommend a friend to use an IUD post abortion.

Indexed as

Abortion, InducedIntrauterine DevicesAdultFemaleFollow-Up StudiesHumansIntrauterine Device ExpulsionPatient SatisfactionPregnancyPregnancy Trimester, SecondTime Factorscontraceptionfamily planning servicesinduced abortionintrauterine device expulsionintrauterine deviceslong‐acting reversible contraceptionrandomized controlled trial

Identifiers

PMID42266170
PMCPMC13394263

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.