GuidelineJournal of the American College of Cardiology2026
2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
Guideline in Journal of the American College of Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Executive Summary of the ASN Kidney Health Guidance on the Cardiovascular‑Kidney‑Metabolic Syndrome.Journal of the American Society of Nephrology : JASN · 2026Guideline
- Cardiometabolic medicine in China: Burden, challenges, and strategic priorities.Metabolism open · 2026Review
- Efficacy and safety of SGLT2 inhibitors in elderly patients with type 2 diabetes.Annals of medicine · 2026Article
- High Prevalence and Limited Perinatal Prediction of Kidney Dysfunction in Adolescents Born Extremely Preterm.Kidney international reports · 2026Article
- Recognition and control gaps in advanced cardiovascular-kidney-metabolic syndrome among United States adults.Preventive medicine reports · 2026Article
- Comparative adverse-event reporting patterns of semaglutide and tirzepatide: a disproportionality analysis of FAERS.Endocrine · 2026Article
- GLP-1-based therapies in cardiovascular disease: outcomes, mechanisms, and emerging clinical applications.European journal of clinical pharmacology · 2026Review
- Cardiovascular-kidney-metabolic syndrome and cancer.Nature reviews. Nephrology · 2026Article
- Cardiorenal Syndrome: From Hemodynamic and Humoral Pathophysiology to New Frontiers in Modulation and Enabling Therapy-Part 1.Biomedicines · 2026Review
- Vascular Phenotyping Across the CKM Syndrome: Arterial Stiffness and Endothelial Function Testing, Prognostic Value and Clinical Implementation.Diagnostics (Basel, Switzerland) · 2026Review
- AI-Enabled Echocardiography Identifies Prominent Epicardial Adipose Tissue Associated With an Adverse Cardiometabolic Profile.medRxiv : the preprint server for health sciences · 2026Article
- Sex and gender in cardiovascular-kidney-metabolic health: strengthening the evidence.Nature reviews. Nephrology · 2026Article
- Trends in prevalence of cardiovascular-kidney-metabolic syndrome stages among US young adults, 2011-2020.American heart journal plus : cardiology research and practice · 2026Article
- Review
- SURPASS-CVOT and the Emerging Biology of Cardiometabolic Benefit.Diabetes, obesity & metabolism · 2026Article
- Reply to Crespo, J.; Iruzubieta, P. Comment on "Orozco-Beltrán et al. Evaluation, Management and Therapeutic Approach of Cardiovascular-Kidney-Metabolic Syndrome: A Multidisciplinary Delphi Expert Consensus.Journal of clinical medicine · 2026Article
- Features of Lipid Disorders in Cardiovascular-Kidney-Metabolic Syndrome.International journal of molecular sciences · 2026Review
- The Functional Side of Multiple Endocrine Neoplasia Type 1-Associated Adrenal Disease: Mild Autonomous Cortisol Secretion.Diseases (Basel, Switzerland) · 2026Article
- Type 2 Diabetes, Visceral Adiposity, and Carotid Intima-Media Thickness in Hospitalized Adults: A Retrospective Cross-Sectional Analysis.Medicina (Kaunas, Lithuania) · 2026Article
- From Specialty Silos to Integrated Care: A Korean Initiative for Cardiovascular-Kidney-Metabolic Health.Electrolyte & blood pressure : E & BP · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
36 authors.
Funding
Abstract
aimThe "2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome" retires, replaces, and expands upon the "2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults." The primary intended audience for this guideline is clinicians who care for patients across the spectrum of cardiovascular-kidney-metabolic syndrome, an interrelated condition characterized by the interconnections among metabolic risk factors (including obesity and type 2 diabetes), chronic kidney disease, and cardiovascular disease.
methodsA comprehensive literature search was conducted from October 29, 2024, to April 14, 2025, to identify clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human subjects that were published since 2015 in English from MEDLINE (through PubMed), EMBASE, the Cochrane Library, the Agency for Healthcare Research and Quality, and other selected databases relevant to this guideline. STRUCTURE: The focus of this clinical practice guideline is to create a living, working document that provides current knowledge in the field of cardiovascular-kidney-metabolic syndrome aimed at all practicing cardiologists, endocrinologists, nephrologists, and primary care and specialty clinicians who manage these patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.