Evidence map›Paper›PMID 42265899›Full record

ReviewJournal of paediatrics and child health2026

Neonatal Acute Kidney Injury-An Australian and New Zealand Perspective.

Saumil Desai, Thomas Forbes, Simon A Carter, Alison L Kent, Chanel Prestidge, David T Selewski, Eveline Staub, Anke Raaijmakers

Abstract readReview
In one paragraph

Review in Journal of paediatrics and child health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Saumil DesaiNewborn Emergency Transport Services, Perth Children's Hospital, Nedlands, Western Australia, Australia.
Thomas ForbesMurdoch Children's Research Institute, Melbourne, Australia.
Simon A CarterMurdoch Children's Research Institute, Melbourne, Australia.
Alison L KentDepartment of Pediatrics, University of Rochester, Rochester, New York, USA.
Chanel PrestidgeDepartment of Paediatric Nephrology, Starship Children's Hospital, Auckland, New Zealand.
David T SelewskiDepartment of Paediatrics, University of Arkansas for Medica Sciences, Little Rock, Arkansas, USA.
Eveline StaubDepartment of Neonatology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.ORCID https://orcid.org/0000-0003-2917-1172
Anke RaaijmakersPaediatric Nephrology, Sydney Children's Hospital, Randwick, Australia.ORCID https://orcid.org/0000-0001-8846-1650

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is increasingly recognized as a critical and underdiagnosed condition among neonates, with significant short and long-term implications for survival, kidney function, and long-term cardiovascular health. Neonatal physiology, including ongoing nephrogenesis, immature renal haemodynamics, and limited glomerular filtration, makes this population vulnerable to AKI. Advances in consensus definitions, particularly the modified neonatal Kidney Disease Improving Global Outcomes (KDIGO) criteria, have enhanced epidemiologic understanding and facilitated global research collaboration. Despite this, significant variability in AKI surveillance, diagnosis, and follow-up persists. Recent research efforts within Australia emphasize the need to incorporate AKI metrics into quality registries and improve equity of kidney care for infants. Integration of protocolized monitoring, preventative strategies such as nephrotoxin stewardship and methylxanthine therapy, and long-term follow-up for AKI survivors are essential to mitigating progression to chronic kidney disease. This narrative review synthesizes evolving evidence in neonatal renal physiology, AKI definition and biomarkers, epidemiology, management, and policy directions, emphasizing opportunities for education, protocol development, and collaborative improvement across Australia, New Zealand and beyond.

Indexed as

Acute Kidney InjuryAustraliaBiomarkersHumansInfant, NewbornNew ZealandBiomarkers

Identifiers

PMID42265899
PMCPMC13480486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.