Evidence map›Paper›PMID 42265711›Full record

ArticleBMC surgery2026

Development and validation of a preoperative nomogram for predicting postoperative high drainage output after robot-assisted Roux-en-Y hepaticojejunostomy for children with choledochal cysts: based on cyst diameter, age, and other indicators.

Jing Zhang, Tao You, Xinke Qin, Chong Liang, Zhenchuang Zhu, Xin Liu, Siqi Ji, Xiaoqiong He, Xufei Duan, Xueqiang Yan

Abstract readValidation Study
In one paragraph

Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

10 authors.

Jing ZhangDepartment of Hepatobiliary and Oncology Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.
Tao YouMedical Department, School of Medicine, Wuhan University of Science and Technology, Wuhan, Hubei, 430070, China.
Xinke QinDepartment of Hepatobiliary and Oncology Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.
Chong LiangDepartment of Hepatobiliary and Oncology Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.
Zhenchuang ZhuDepartment of Hepatobiliary and Oncology Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.
Xin LiuDepartment of Hepatobiliary and Oncology Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.
Siqi JiDepartment of Hepatobiliary and Oncology Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.
Xiaoqiong HeDepartment of Hepatobiliary and Oncology Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.
Xufei DuanDepartment of Hepatobiliary and Oncology Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China.
Xueqiang YanDepartment of Hepatobiliary and Oncology Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430016, China. yanxueqiang1@163.com.

Funding

the Laboratory of Hepatobiliary and Pancreatic Diseases in Children 2025FEYJS005
6 · The paper itself

Abstract

backgroundRobot-assisted Roux-en-Y hepaticojejunostomy (RYHJ) is the standard treatment for choledochal cysts (CDC). Routine abdominal drainage is typically placed, but no reliable preoperative tool exists to identify patients at risk of high drainage output (≥ 2 mL·kg⁻

methodsThis single-center retrospective cohort study enrolled 129 children with CDC who underwent da Vinci robot-assisted RYHJ. Based on weight-adjusted daily drain output, patients were divided into low-drainage (< 2 mL·kg⁻

resultsMultivariate analysis identified younger age as an independent predictor of high drainage output (OR = 0.983, 95% CI: 0.972-0.994), and larger cyst diameter as a potential predictor showing a trend toward association (OR = 1.321, 95% CI: 0.979-1.783). The final nomogram, incorporating cyst diameter, age, body mass index (BMI), hemoglobin (HGB), and globulin (GLB), showed good discrimination (AUC = 0.753) and calibration. The optimal risk threshold was 79.88%, yielding a specificity of 75.9%, and, using an optimal threshold, identifies low-risk patients suitable for early drain removal protocols to guide individualized drainage management.

conclusionWe have developed and validated a nomogram model based on "cyst diameter + age" (supplemented by BMI, HGB, and GLB) that enables noninvasive, precise assessment of high-drainage risk following robot-assisted RYHJ. Notably, the model identifies a low-risk subset-older children with smaller cysts-for whom early drain removal (e.g., within 24-48 h) is safe, and in whom selective drain omission could be prospectively evaluated under rigorous monitoring. This risk-stratified approach has the potential to reduce drain-related complications and optimize ERAS pathways following robot-assisted RYHJ. As this is an internal validation only, external validation in independent cohorts is warranted before clinical implementation.

Indexed as

Anastomosis, Roux-en-YCholedochal CystDrainageJejunostomyNomogramsPostoperative ComplicationsRobotic Surgical ProceduresAge FactorsChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesCholedochal cyst (CDC)Enhanced recovery after surgery (ERAS)High drainage outputNomogramPediatric surgeryRobot-assisted Roux-en-Y hepaticojejunostomy (RYHJ)

Identifiers

PMID42265711
PMCPMC13474786

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