Evidence map›Paper›PMID 42265613›Full record

ArticleBMC microbiology2026

Eucommia ulmoides leaves improving growth by regulating the rumen microbiome in sheep.

Yehao Hu, Lijuan Pan, Boshuai Liu, Chuanyou Su, Liyang Zhang, Wenjuan Li, Tong Fu, Tengyun Gao, Hongxia Lian, Linfeng Wang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yehao Hu *Henan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.ORCID http://orcid.org/0009-0004-9783-8674
Lijuan Pan *Henan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.ORCID http://orcid.org/0009-0001-2798-7015
Boshuai LiuHenan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.
Chuanyou SuHenan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.
Liyang ZhangHenan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.
Wenjuan LiHenan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.
Tong FuHenan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.
Tengyun GaoHenan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.
Hongxia LianHenan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.
Linfeng WangHenan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China.
Yangdong ZhangState Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100193, People's Republic of China. zhangyangdong@caas.cn.ORCID http://orcid.org/0000-0002-5256-0531
Kaizhen LiuHenan International Joint Laboratory of Nutrition Regulation and Ecological Raising of Domestic Animal, College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China. liukaizhen@henau.edu.cn.ORCID http://orcid.org/0000-0002-1364-0061

Funding

Henan Province Science and Technology Research Project (2025) 252102110017Key technologies for efficient utilization of cattle and sheep feed and forage and carbon emission reduction 2024YFD1300204
6 · The paper itself

Abstract

backgroundRuminants have the ability to convert agricultural byproducts into valuable resources. However, the influence of functional roughage with medicinal value on production performance and rumen function in ruminants remains unclear. This study aimed to examine the role of Eucommia ulmoides leaves (EUL) in the growth performance and rumen microbiome of sheep.

resultsTwenty-one healthy female sheep were randomly divided into three groups, in which the EUL feeding amounts were 0% (CON), 5% (Diet 1), and 10% (Diet 2) on a dry matter basis. The results revealed that body weight gain, dry matter intake, and feed conversion efficiency were significantly greater in the Diet 1 group than in the CON and Diet 2 group. The metatranscriptome annotation results indicated that feeding EUL to sheep altered the rumen microbial community. Compared with those in the other two groups, the abundances of butyrate-producing bacteria, such as Coprobacillus, significantly increased in the Diet 1 group. Functional enrichment analysis of the metatranscriptome indicated higher metabolic activity in the carbohydrate and amino acid pathways in the Diet 1 group than in the control group, which might be due to improved nutrient utilization in the Diet 1 group.

conclusionsIn conclusion, feeding 5% EUL to sheep enhanced production performance, feed conversion efficiency, and microbial metabolism. These findings suggest that EUL plays a critical role in sustainable livestock farming as a promising functional roughage.

Indexed as

BacteriaEucommiaceaeGastrointestinal MicrobiomePlant LeavesRumenAnimal FeedAnimalsDietFemaleSheepEucommia ulmoides leavesMicrobiomeProduction performanceSheepVolatile fatty acids

Identifiers

PMID42265613
PMCPMC13543632

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.