Evidence map›Paper›PMID 42265211›Full record

ArticleNature methods2026

Spatially resolved m

Yu Xiao, Zhiliang Bai, Zhuoning Zou, Chang Ye, Bo Tao, Zhong Zheng, Yan-Ming Chen, Zhongyu Zou, Liudan Jiang, Lijie Zhao and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature methods, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yu Xiao *Department of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-8012-8121
Zhiliang Bai *Department of Biomedical Engineering, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-3977-3057
Zhuoning Zou *Department of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-7984-7121
Chang YeDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-0236-5671
Bo TaoDepartment of Pathology, Yale University School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-5490-4668
Zhong ZhengDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Yan-Ming ChenDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-0783-5169
Zhongyu ZouDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-7152-5435
Liudan JiangDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Lijie ZhaoDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0002-0490-0175
Yuhang FanDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Yun GaoDepartment of Chemistry, The University of Chicago, Chicago, IL, USA.
Rong FanDepartment of Biomedical Engineering, Yale University, New Haven, CT, USA. rong.fan@yale.edu.ORCID http://orcid.org/0000-0001-7805-8059
Chuan HeDepartment of Chemistry, The University of Chicago, Chicago, IL, USA. chuanhe@uchicago.edu.ORCID http://orcid.org/0000-0003-4319-7424

Funding

Spatiotemporal Tumor Analytics for Guiding Sequential Targeted-Inhibitor: Immunotherapy Combinations (ST-Analytics)U54CA274509 · NCI · INSTITUTE FOR SYSTEMS BIOLOGY · PI Rong Fan · 2022 to 2026
$15.6M
Yale TMC for Cellular Senescence in Lymphoid OrgansU54AG076043 · NIA · YALE UNIVERSITY · PI FAN, RONG, HALENE, STEPHANIE · 2021 to 2025
$7.0M
Yale Murine-TMC on Immune Cell Senescence Derived InflammationU54AG079759 · NIA · YALE UNIVERSITY · PI DIXIT, VISHWA DEEP, MONTGOMERY, RUTH R · 2022 to 2025
$6.5M
Highly scalable and sensitive spatial transcriptomic and epigenomic sequencing of brain tissues from human and non-human primateRF1MH128876 · NIMH · YALE UNIVERSITY · PI FAN, RONG, SESTAN, NENAD · 2021 to 2021
$2.9M
Ex vivo analysis of human brain tumor cells in a microvascular niche modelR01CA245313 · NCI · YALE UNIVERSITY · PI FAN, RONG, ZHOU, JIANGBING · 2020 to 2024
$2.6M
High-spatial-resolution ECM-inclusive multi-omics sequencing of human PFA and FFPE tissue slidesUH3CA257393 · NCI · YALE UNIVERSITY · PI FAN, RONG · 2022 to 2023
$1.2M
Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) R01HG013495Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) RC2DK139552Foundation for the National Institutes of Health (Foundation for the National Institutes of Health, Inc.) RM1HG008935U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R01CA245313U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) U54CA274509U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) UH3CA257393U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH) RF1MH128876U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) U54AG076043U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) U54AG079759
6 · The paper itself

Abstract

N

Indexed as

AdenosineAnimalsBrainEpitranscriptomeEpitranscriptomicsGene Expression ProfilingHippocampusMiceRNA MethylationTranscriptomeAdenosineN-methyladenosine

Identifiers

PMID42265211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.