Evidence map›Paper›PMID 42265103›Full record

Articlenpj aging2026

Disentangling shifting demographic and treatment effects on years of life lost to cancer in Denmark.

Ólafur Birgir Davíðsson, Emelie Hamotal Curovic-Rotbain, Ragnar Pétur Kristjánsson, Jojo Biel-Nielsen Dietz, Signe Holst Søegaard, Mikkel Werling, Fie Stegenborg Andersen, Susanne Dalton, Carsten Utoft Niemann, Mads Melbye and 3 more

Abstract read
In one paragraph

Article in npj aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Antifungal Dispensing in Denmark: Patterns Across Primary Care, Secondary Care, and Over-the-Counter Sectors.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ólafur Birgir DavíðssonDanish Cancer Institute, Hematology, Copenhagen, Denmark. olafur@frameshift.dk.
Emelie Hamotal Curovic-RotbainDanish Cancer Institute, Hematology, Copenhagen, Denmark.
Ragnar Pétur KristjánssonDanish Cancer Institute, Hematology, Copenhagen, Denmark.
Jojo Biel-Nielsen DietzDanish Cancer Institute, Hematology, Copenhagen, Denmark.
Signe Holst SøegaardDanish Cancer Institute, Hematology, Copenhagen, Denmark.
Mikkel WerlingDanish Cancer Institute, Hematology, Copenhagen, Denmark.
Fie Stegenborg AndersenDanish Cancer Institute, Cancer Survivorship, Copenhagen, Denmark.
Susanne DaltonDanish Cancer Institute, Cancer Survivorship, Copenhagen, Denmark.
Carsten Utoft NiemannDanish Cancer Institute, Hematology, Copenhagen, Denmark.
Mads MelbyeDanish Cancer Institute, Copenhagen, Denmark.
Søren FriisDanish Cancer Institute, Cancer Epidemiology and Monitoring, Copenhagen, Denmark.
Henrik HjalgrimDanish Cancer Institute, Hematology, Copenhagen, Denmark.
Klaus RostgaardDanish Cancer Institute, Hematology, Copenhagen, Denmark.

Funding

Kræftens Bekæmpelse R325-A18705 and R374-A22191
6 · The paper itself

Abstract

Cancer is increasingly relevant to ageing societies, yet progress in cancer control is difficult to assess when population years of life lost (YLL) to cancer appear stable. Using Danish registers, we followed 4.26 million residents aged ≥50 years (1980-2019) and estimated YLL under observed and counterfactual scenarios, separating demography and incidence from post-diagnosis outcomes. From the 1980s to the 2010s, YLL per individual changed little (men 2.3 to 2.1; women 2.5 to 2.2), while YLL per patient fell markedly (men 8.5 to 5.2; women 9.3 to 5.8). With 2010s incidence and background mortality but 1980s management, YLL per individual would have been 4.2 (men) and 3.9 (women), showing that cancer control averted about half of the life-years otherwise lost. YLL reductions were largest for localized and regional disease (~60 and ~40%) and modest for distant stage (~15%), highlighting persistent losses in advanced cancer and growing survivorship-care needs.

Identifiers

PMID42265103
PMCPMC13590599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.