Evidence map›Paper›PMID 42265056›Full record

SynthesisEpidemiology and psychiatric sciences2026

Social inclusion inequalities between individuals with mental disorders and the general population: a systematic review and meta-analysis.

Giulia Pollice, Mattia Marchi, Maria Trapani, Alice Pagnucco, Silvia Ferrari, Luca Ghirotto, Luca Pingani, Gian Maria Galeazzi

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Epidemiology and psychiatric sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giulia PolliceDepartment of Biomedical, Metabolic and Neural Science, University of Modena and Reggio Emilia, Modena, Italy.ORCID https://orcid.org/0009-0005-1625-187X
Mattia MarchiDepartment of Biomedical, Metabolic and Neural Science, University of Modena and Reggio Emilia, Modena, Italy.ORCID https://orcid.org/0000-0003-2970-1276
Maria TrapaniDipartimento ad Attività Integrata Salute Mentale e Dipendenze Patologiche, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Alice PagnuccoDepartment of Philosophy, Sociology, Education and Applied Psychology, University of Paduahttps://ror.org/00240q980, Padua, Italy.
Silvia FerrariDepartment of Biomedical, Metabolic and Neural Science, University of Modena and Reggio Emilia, Modena, Italy.
Luca GhirottoQualitative Research Unit, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.ORCID https://orcid.org/0000-0001-7632-1271
Luca PinganiDepartment of Biomedical, Metabolic and Neural Science, University of Modena and Reggio Emilia, Modena, Italy.ORCID https://orcid.org/0000-0003-3428-8308
Gian Maria GaleazziDepartment of Biomedical, Metabolic and Neural Science, University of Modena and Reggio Emilia, Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsSocial inclusion is increasingly recognised as a key determinant of health and well-being, encompassing participation in social, economic, political and cultural life through access to resources, opportunities and relationships. Individuals with mental disorders are at increased risk of social exclusion, yet existing evidence often relies on broad population-level indicators that fail to capture the multidimensional nature of inclusion. This systematic review aimed to compare levels of social inclusion between these groups using validated psychometric instruments and to identify the dimensions in which disparities are most pronounced.

methodsThe review followed PRISMA guidelines. A two-step search strategy was conducted across PubMed, Embase, PsycINFO, Scopus, CINAHL and Web of Science. First, validated measures of social inclusion and related constructs were identified. Second, studies applying these instruments in individuals with and without mental disorders were retrieved. Eligible studies included adults with clinician-established or self-reported diagnosis of mental disorders and comparison groups from the general population. A random-effects meta-analysis was conducted to estimate standardised mean differences (SMDs) with 95% confidence intervals (CIs) between the two groups, while a thematic narrative synthesis explored domain-specific inequalities.

resultsTen studies met inclusion criteria, and six were included in the meta-analysis, comprising 844 individuals with mental disorders and 1086 controls. Individuals with mental disorders reported significantly lower levels of social inclusion than the general population (SMD = -0.91; 95% CI: -1.25 to -0.56). The narrative synthesis identified inequalities across several interconnected domains. Individuals with mental disorders experienced weaker social relationships, lower perceived support, reduced community participation and fewer opportunities for meaningful engagement. Marked disadvantages were also observed in employment, income, education and housing, including financial hardship, insecure living conditions and neighbourhood dissatisfaction. Several studies highlighted discrepancies between objective indicators of participation and subjective experiences of inclusion, indicating that participation alone may not reflect a sense of belonging or access to valued social roles. Socioeconomic position, gender and ethnicity appeared to intensify exclusion across domains.

conclusionsIndividuals with mental disorders experience substantial inequalities in social inclusion across interconnected relational, community and socioeconomic domains. These disparities are shaped by broader structural conditions and compounded by intersecting forms of disadvantage, including socioeconomic position, gender and ethnicity. The findings highlight the need for multidimensional, intersectional and person-centred approaches that recognise both the cumulative nature of exclusion and individuals' subjective experiences of inclusion. Policies and interventions should address the social determinants that constrain opportunities for meaningful inclusion.OSF: https://doi.org/10.17605/OSF.IO/USXWG.

Indexed as

Mental DisordersSocial InclusionHumansSocioeconomic Disparities in HealthSocioeconomic Factorscommunity mental healthepidemiologysocial factorssocial inclusionsystematic reviews

Identifiers

PMID42265056
PMCPMC13276723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.