Trial reportDiabetes, obesity & metabolism2026
Pre-Exercise Galactose or Lactose Reduces Glycaemic Excursions During Exercise in Adults With Type 1 Diabetes: A Randomised, Double-Blind, Crossover Trial.
Trial report in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05557227 (Galactose - the Ideal Carbohydrate Supplement for Exercise in Type 1 Diabetes), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Galactose - the Ideal Carbohydrate Supplement for Exercise in Type 1 Diabetes
Who cites it
1 citing paper in PubMed.
- Pre-Exercise Galactose or Lactose Reduces Glycaemic Excursions During Exercise in Adults With Type 1 Diabetes: A Randomised, Double-Blind, Crossover Trial.Diabetes, obesity & metabolism · 2026Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
aimsTo test whether pre-exercise galactose and lactose reduce glycaemic excursions during exercise compared with dextrose while maintaining protection against hypoglycaemia compared with placebo in adults with Type 1 diabetes
methodsIn a randomised, double-blind, 4-condition crossover trial, 14 adults with Type 1 diabetes completed four 60-min cycling sessions. Thirty minutes before exercise, participants consumed 20 g of dextrose, lactose, galactose, or placebo. The primary outcome was time to hypoglycaemia. Secondary outcomes included time in, below, and above range and glucose excursions.
resultsSeven hypoglycaemic events occurred (none after dextrose, two after lactose, one after galactose, and four after placebo; p = 0.42), with no difference in time to hypoglycaemia. Time in range was lower for dextrose (48% [95% CI 40-57]) compared with lactose (70% [95% CI 62-78]), galactose (71% [95% CI 63-79]), and placebo (86% [95% CI 80-91]) (all p ≤ 0.01). Time below range was lower for dextrose (0% [95% CI 0-3]), lactose (1% [95% CI 0-5]), and galactose (1% [95% CI 0-5]) compared with placebo (8% [95% CI 4-14]) (all p < 0.05). Time above range was higher for DEX (52% [95% CI 44-60]), LAC (29% [95% CI 21-37]), and GAL (28% [95% CI 21-36]) compared with PLA (7% [95% CI 3-12], all p < 0.01).
conclusionsPre-exercise galactose and lactose provide more stable glycaemic responses than dextrose and reduce time below range compared with placebo. These findings support their use as effective pre-exercise nutritional strategies in individuals with Type 1 diabetes.
trial registrationClinicalTrials.gov identifier: NCT05557227.
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