Evidence map›Paper›PMID 42264484›Full record

Observational studyHospital pediatrics2026

Nasogastric Hydration Utilization in Bronchiolitis, an EMO Trial Observational Substudy.

Brandy M Hoyt, Jacob Thomas, Amy Tyler, Elizabeth Temte, Morgan McMahon, John D Watson, Christopher P Bonafide, Rinad S Beidas, Rui Xiao, Enrique F Schisterman and 2 more

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Hospital pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Brandy M HoytDepartment of Pediatrics, Section of Hospital Medicine, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.
Jacob ThomasAdult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado, Aurora, Colorado.
Amy TylerDepartment of Pediatrics, Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, Ohio.
Elizabeth TemteDepartment of Pediatrics, Section of Hospital Medicine, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.
Morgan McMahonDepartment of Pediatrics, Section of Hospital Medicine, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.
John D WatsonDepartment of Pediatrics, Section of Hospital Medicine, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.
Christopher P BonafideSection of Hospital Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Rinad S BeidasDepartment of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Rui XiaoDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Enrique F SchistermanDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Michael J TchouDepartment of Pediatrics, Section of Hospital Medicine, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado.
Pediatric Research in Inpatient Settings (PRIS) Network

Funding

Eliminating Monitor Overuse (EMO) Hybrid Effectiveness-Deimplementation TrialU01HL159880 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI BEIDAS, RINAD SARY, BONAFIDE, CHRISTOPHER PETER · 2021 to 2025
$5.3M
NHLBI NIH HHS U01 HL159880
6 · The paper itself

Abstract

backgroundNasogastric (NG) fluid replacement is an effective and nutritionally beneficial alternative to intravenous (IV) hydration for pediatric inpatients with bronchiolitis. Existing evidence demonstrates equipoise in the use of NG vs IV hydration; however, interinstitutional data on NG hydration utilization are lacking.

objectivesTo describe NG hydration in bronchiolitis across institutions and its association with clinical factors and outcomes.

methodsThis observational multicenter substudy of the Eliminating Monitor Overuse (EMO) Trial collected data on fluid replacement for pediatric inpatients. Children aged 2 through 23 months with bronchiolitis between January and May 2023 were included. Those with extreme prematurity, apnea or cyanosis, or comorbid conditions that could impact pulse oximetry use were excluded. We measured NG and IV utilization rates over all encounters and then measured institution-specific rates in patients receiving either NG or IV hydration. Maximum respiratory support, intensive care unit (ICU) stay, and neurologic impairment (NI) were compared between NG and IV cohorts. Multivariable models examined factors associated with NG hydration and length of stay (LOS).

resultsOur substudy included 1707 observations from 33 hospitals. Overall NG utilization was 7%, and IV use was 52%. Among patients who received either NG or IV hydration, institution-specific NG utilization ranged from 0% to 70%. Patients on mechanical ventilation, in the ICU, and with NI were more likely to receive NG hydration. LOS was 1.83-fold longer (95% CI, 1.62-2.06) for patients who received NG compared with IV hydration.

conclusionsWe found overall low use of NG hydration, with wide between-hospital variation. Children who experienced critical illness and NI were more likely to receive NG hydration.

Indexed as

BronchiolitisFluid TherapyIntubation, GastrointestinalFemaleHumansInfantLength of StayMale

Identifiers

PMID42264484
PMCPMC13256195

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.