Evidence map›Paper›PMID 42264281›Full record

ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2026

Approach to prevention and management of chronic lung allograft dysfunction in North American lung transplant centers.

Siddhartha G Kapnadak, Tijana Milinic, Eric D Morrell, William Brandon, Megan Mayer, Sierra Knapp, Lianne G Singer, Albert Faro, Joseph M Pilewski, Christopher H Goss and 4 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Siddhartha G KapnadakDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA. Electronic address: skap@uw.edu.
Tijana MilinicDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA.
Eric D MorrellDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA; Veterans Affairs Puget Sound Health Care System, Seattle, WA.
William BrandonDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA.
Megan MayerDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA.
Sierra KnappDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA.
Lianne G SingerDivision of Respirology, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Albert FaroCystic Fibrosis Foundation, Bethesda, MD.
Joseph M PilewskiDivision of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Christopher H GossDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA; CF Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, WA; Division of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Washington, Seattle, WA.
Nicole Mayer-HamblettCF Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, WA; Division of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Washington, Seattle, WA; Department of Biostatistics, University of Washington, Seattle, WA.
Ramsey HachemDivision of Division of Respiratory, Critical Care, and Occupational Pulmonary Medicine, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT.
Kathleen J RamosDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA; CF Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, WA.
CF Lung Transplant Initiative Investigators

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss · 2010 to 2026
$21.4M
Preparation for lung transplant discussions and decisions among people with cystic fibrosisR01NR020470 · NINR · UNIVERSITY OF WASHINGTON · PI Kathleen Jessica Ramos · 2023 to 2026
$2.9M
Alveolar macrophage subset ontogeny and differentiation during ARDSR01HL169265 · NHLBI · UNIVERSITY OF WASHINGTON · PI Eric Douglas Morrell · 2024 to 2026
$2.1M
NHLBI NIH HHS R01 HL169265NIDDK NIH HHS P30 DK089507NINR NIH HHS R01 NR020470
6 · The paper itself

Abstract

Chronic lung allograft dysfunction (CLAD) is the major barrier to long-term survival after lung transplantation, but literature documenting contemporary practice patterns and best practices for management are lacking. We sought to characterize monitoring and lung function-dependent management strategies across adult North American lung transplant centers. A RedCap survey was distributed to 21 centers accounting for nearly half of North American lung transplants. Routine immunosuppression and post-transplant graft monitoring protocols were similar among centers. Prophylactic azithromycin was routinely used by 7 (33.3%) centers, and respondents had substantial uncertainty regarding its effectiveness. A persistent ≥10% FEV

Indexed as

Disease ManagementGraft RejectionLung TransplantationPrimary Graft DysfunctionAllograftsAzithromycinChronic DiseaseFemaleHumansImmunosuppressive AgentsNorth AmericaAzithromycinImmunosuppressive AgentsazithromycinChronic lung allograft dysfunctionImmunosuppressionlung transplantationpractice patterns

Identifiers

PMID42264281
PMCPMC13334939

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.