Evidence map›Paper›PMID 42263111›Full record

ArticleJournal of cardiovascular electrophysiology2026

Impacts of Hemodynamic Support on Ventricular Arrhythmia Ablation.

Denise Guckel, Moneeb Khalaph, Mustapha El Hamriti, Thomas Fink, Vanessa Sciacca, Maximilian Moersdorf, Guram Imnadze, Martin Braun, Angelika Costard-Jäckle, René Schramm and 3 more

Abstract readComparative Study
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Denise GuckelClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Moneeb KhalaphClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Mustapha El HamritiClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Thomas FinkClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Vanessa SciaccaClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Maximilian MoersdorfClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Guram ImnadzeClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Martin BraunClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Angelika Costard-JäckleClinic for Thoracic and Cardiovascular Surgery, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
René SchrammClinic for Thoracic and Cardiovascular Surgery, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Jan GummertClinic for Thoracic and Cardiovascular Surgery, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Philipp SommerClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
Christian SohnsClinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.ORCID 0000-0003-0490-5862

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundData on the efficacy of hemodynamic support (HS) for protecting ventricular arrhythmia (VA) ablation in high-risk heart failure (HF) patients with an impaired left ventricular function and its impact on mortality is limited.

objectivesThis study aimed to assess procedural efficacy, related complications, VA-free survival, and mortality of HF patients who underwent protected VA ablation with HS.

methodsData from consecutive HF patients undergoing VA ablation at our center between 2018 and 2024 were analyzed. HS included the treatment with an Impella, an extracorporeal membrane oxygenation (ECMO) or a left ventricular assist device (LVAD). Patients were classified based on their HF status according to current guidelines.

resultsA total of 187 patients (61.5 ± 10.9 years) were included. 124/187 patients were in advanced HF (66%, 63.5 ± 8.9 years). In 68/187 patients (36%, 60.8 ± 9.8 years), HS was required. Procedural parameter did not differ between the groups except for fluoroscopy times (p < 0.001). Acute procedural success (p = 0.670) and major procedure-related complications (p = 0.726) were comparable. In-hospital mortality was higher in patients with HS (p < 0.001). In advanced HF patients, freedom from VA-recurrence was lower (p = 0.016) and mortality higher (p = 0.009). HS with an ECMO and LVAD, but not with an Impella, was associated with increased VA-recurrence (hazard ratio [HR] 3.66, confidence Interval [CI] 1.732-7.715, p < 0.001) and mortality (HR 3.95, CI 1.091-14.280, p = 0.036).

conclusionIn high-risk HF patients, VA ablation was feasible with comparable acute success and procedural complication rates. Patients with ECMO or LVAD showed higher in-hospital mortality and higher VA recurrence compared to Impella-supported procedures, likely reflecting more advanced disease severity rather than differences in procedural efficacy.

Indexed as

Catheter AblationExtracorporeal Membrane OxygenationHeart-Assist DevicesHeart FailureHemodynamicsTachycardia, VentricularVentricular Dysfunction, LeftVentricular Function, LeftAgedFemaleHeart RateHospital MortalityHumansMaleMiddle AgedProgression-Free Survivalablationheart failurehemodynamic supportmortalityventricular arrhythmias

Identifiers

PMID42263111
PMCPMC13475177

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.