Comparison of fat-suppression-related sequence operations for stiffness stability in spin-echo echo-planar imaging magnetic resonance elastography: a phantom study.

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Article in Radiological physics and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 authors.

Yuuki YoshimuraDepartment of Radiological Technology, Okayama Saiseikai General Hospital, 2-25 Kokutai-cho, Kita-ku, Okayama, Okayama, 700-8511, Japan. yuukiyoshimura0212@gmail.com.ORCID http://orcid.org/0000-0001-9739-9959

Kohei SugimotoDepartment of Radiological Technology, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare, 288 Matsushima, Kurashiki, Okayama, 701-0193, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spin-echo echo-planar imaging (SE-EPI)-based magnetic resonance elastography (MRE) is susceptible to chemical shift artifacts, making sequence-related operations important for stable measurements. This phantom study evaluated the influence of fat-suppression-related sequence operations on stiffness measurement variability in SE-EPI MRE. Imaging was performed at 3-T under six conditions, with five repeated acquisitions and four slices per scan. Mean stiffness, variability, and measurable area were assessed using the average coefficient of variation (aCV), and signal-to-noise ratio (SNR) was quantitatively evaluated. All conditions yielded stiffness values within the expected range. Spectral attenuated inversion recovery with strong showed the lowest aCV (0.7%), whereas water excitation showed the highest aCV (6.0%) and the smallest measurable area. Sequence-related differences were associated with variability, suggesting contributions from SNR and sequence-dependent signal characteristics affecting stiffness stability.

Indexed as

Adipose TissueEcho-Planar ImagingElasticity Imaging TechniquesImage Processing, Computer-AssistedPhantoms, ImagingSignal-To-Noise RatioChemical shiftFat-suppression–related sequence operationsMagnetic resonance elastographyPhantom studySpin-echo echo-planar imagingStiffness stability

Identifiers

PMID42262635

DOI10.1007/s12194-026-01078-2

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.