Evidence map›Paper›PMID 42262566›Full record

ArticleMikrochimica acta2026

Enhanced Fenton and Fenton-like reactions via heteroatoms doping in Co/Fe Co-doped carbon dots for ultrasensitive H₂O₂ detection with dual-mode fluorescence and smartphone-based sensing.

Shaimaa Abubakr Abdalla, Khalid M Omer, Shilan A Fatah

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Article in Mikrochimica acta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 authors.

Shaimaa Abubakr AbdallaDepartment of Chemistry, College of Science, University of Charmo, Chamchamal, Kurdistan Region, 46023, Iraq.
Khalid M OmerDepartment of Chemistry, College of Science, University of Sulaimani, Sulaymaniyah, Kurdistan Region, 46002, Iraq. khalid.omer@univsul.edu.iq.
Shilan A FatahDepartment of Pharmacy, Kurdistan Technical Institute, Sulaimani, KGR, 46001, Iraq.

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6 · The paper itself

Abstract

Heteroatom doping has emerged as an effective strategy to tailor the electronic structure and enhance the functional properties of carbon dots for sensing applications. In this work, Co and Fe co-doped carbon dots (Co/Fe-CDs) were synthesized via a one-pot hydrothermal method and used as a sensing probe for the detection of hydrogen peroxide (H₂O₂). The Co/Fe-CDs exhibited a high photoluminescence quantum yield of 36%, exceeding that of their mono-doped counterparts (Fe-CDs and Co-CDs), along with stable emission at 410 nm (upon excitation at 340 nm) that was maintained for up to two weeks in solution. The emission was quenched upon the addition of H₂O₂, enabling the design of an on-off probe for H₂O₂ sensing. Characterization confirms the successful synthesis and incorporation of Fe and Co into the carbon dot structure. Mechanistic investigations revealed that the fluorescence quenching process is governed by Fenton and Fenton-like reaction mechanisms and is induced by surface oxidation facilitated by the catalytic redox activity of Co and Fe surface states. The Co/Fe-CD-based sensor exhibited a broad linear response range from 10 to 500 µM, with a low limit of detection (LOD) of 2.79 µM. To enhance the practical applicability of the sensor for point-of-care testing, a smartphone-based detection platform was developed. By analyzing the blue-channel intensity of fluorescence images captured under UV illumination, a linear detection range of 25-400 µM was achieved, with a LOD of 7.11 µM. The proposed method was successfully applied to the determination of H₂O₂ in commercial and medical samples, yielding excellent recoveries (97.94-103.43%) and high selectivity toward common interfering species. These results demonstrate that the developed Co/Fe-CD-based sensor is a promising, portable, and robust platform for real-time H₂O₂ monitoring in a wide range of applications.

Indexed as

Carbon dotsCo/Fe-doped carbon dotsFenton-based carbon dotsFluorometric detectionSmartphone-assisted colorimetric detection

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