ArticleClinical research in cardiology : official journal of the German Cardiac Society2026
Response in renal function after transcatheter tricuspid edge-to-edge repair.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundChronic kidney disease (CKD) frequently coexists with heart failure (HF) and is associated with worse renal outcomes, due to venous congestion and reduced renal perfusion. In patients with severe tricuspid regurgitation (TR), transcatheter tricuspid edge-to-edge repair (T-TEER) can relieve symptoms, but its renal effects across CKD stages remain insufficiently defined. This study assessed changes in renal function, congestion markers, and acute kidney injury (AKI) before and after T-TEER.
methodsThis retrospective single-center study included 181 consecutive patients who underwent T-TEER at Robert Bosch Hospital Stuttgart between March 2021 and February 2023. Follow-up (median 125 days, IQR 6-506; up to 1280 days) was based on complete routine EHR (electronic health records) data. Patients with insufficient information were excluded.
resultsRenal function improved significantly after T-TEER (median eGFR + 4.8 mL/min/1.73 m
conclusionsPost-T-TEER, improvements in renal and congestion parameters were observed, accompanied by a lower incidence of AKI across CKD stages. These findings suggest a potential association between T-TEER and improvment in renal function and congestion. In patients with severe TR, T-TEER may be associated with preservation of kidney function and a reduced risk of AKI.
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