Evidence map›Paper›PMID 42262416›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2026

Differences in Antibiotic Prescribing Patterns for Children with Acute Otitis Media Based on Patient, Clinician, and Clinic Characteristics.

Alexander S Plattner, Sonja O'Leary, Sophie E Katz, Leisha M Andersen, Evan E Facer, Timothy C Jenkins, Amy B Stein, Gale Thomas, Nancy Koenig, Holly M Frost and 1 more

Abstract read
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexander S PlattnerWashU Medicine, Department of Pediatrics, Division of Infectious Diseases, St. Louis, MO, United States.ORCID 0000-0002-6353-9439
Sonja O'LearyDenver Health Medical Center, Department of General Pediatrics, Denver, CO, United States.
Sophie E KatzVanderbilt University Medical Center, Department of Pediatrics, Division of Infectious Diseases, Nashville, TN, United States.
Leisha M AndersenAmerican Academy of Pediatrics, Colorado Chapter, Englewood, CO, United States.
Evan E FacerWashU Medicine, Department of Pediatrics, Division of Infectious Diseases, St. Louis, MO, United States.
Timothy C JenkinsDenver Health and Hospital Authority, Department of Medicine, Division of Infectious Diseases, Denver, CO, United States.
Amy B SteinDenver Health and Hospital Authority, Center for Health Systems Research, Denver, CO, United States.
Gale ThomasVanderbilt University Medical Center, Department of Pediatrics, Division of Infectious Diseases, Nashville, TN, United States.
Nancy KoenigWashU Medicine, Department of Pediatrics, Division of Infectious Diseases, St. Louis, MO, United States.
Holly M FrostIntermountain Health, Office of Research, Salt Lake City, UT, United States.ORCID 0000-0002-3016-3287
RELAX Study Group

Funding

Pediatric Infectious Diseases and Immunity Training ProgramT32AI106688 · NIAID · WASHINGTON UNIVERSITY · PI Megan Anne Cooper, DAVID HUNSTAD · 2014 to 2026
$1.9M
AHRQ HHS 1R01HS029153-01AHRQ HHS R01 HS029153NIAID NIH HHS T32 AI106688U.S. Department of Health and Human Services
6 · The paper itself

Abstract

objectivesChildren with common infections receive varying care based on their backgrounds; however, data for acute otitis media (AOM) management are limited. Our study aimed to evaluate differences in antibiotic prescribing rate and treatment duration for children (≥2 years) with uncomplicated AOM based on patient, clinician, and clinic characteristics.

methodsRetrospective study of health record data from two health systems (123 total sites) from 2019 to 2022. Primary outcomes included: (1) whether an antibiotic was prescribed, and (2) if so, the duration prescribed. Analyses were performed to assess whether differences in prescribing occurred among individual patients, clinicians, or clinics.

resultsAmong 66,382 encounters for AOM, children who were races other than White, Hispanic, or had public insurance or self-pay were more likely to be prescribed an antibiotic than children who were White (87% vs. 83%, OR 1.43 [1.12, 1.84]), non-Hispanic (88% vs. 82%, OR 1.54 [1.06, 2.23]), or had commercial/private insurance (87% vs. 83%, OR 1.35 [1.10, 1.67]). The mean treatment duration was ~9 days for all groups, however statistical significance was seen with shorter courses for children who were races other than White, Hispanic, had a primary language other than English, or had public insurance or self-pay. Duration differences were seen among clinicians, with those who prescribed the shortest durations seeing, on average, a greater proportion of children who were races other than White, Hispanic, spoke a non-English primary language, and had public insurance or self-pay.

conclusionsChildren with AOM who were races other than White, Hispanic, or had public insurance or self-pay were more likely to be prescribed an antibiotic. However, shorter durations were more common among these children, primarily because clinicians serving this population tended to prescribe shorter durations to all patients, regardless of child sociodemographic characteristics.

Indexed as

Anti-Bacterial AgentsDrug PrescriptionsOtitis MediaPractice Patterns, Physicians'Acute DiseaseAdolescentChildChild, PreschoolDuration of TherapyFemaleHumansInfantMaleRetrospective StudiesAnti-Bacterial Agentsacute otitis mediaantibiotic stewardshipduration of therapypediatrics

Identifiers

PMID42262416
PMCPMC13393534

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.