Evidence map›Paper›PMID 42262158›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Derivation and Validation of a Genotype- Guided Warfarin Dosing Model in a Mixed Arab Population.

Amr M Fahmi, Ahmed El Bardissy, Mohamed Omar Saad, Islam Eljilany, Loulia Bader, Hazem Elewa

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amr M FahmiPharmacy Department, Hamad Medical Corporation, Doha, Qatar.ORCID 0000-0002-1502-6700
Ahmed El BardissyPharmacy Department, Hamad Medical Corporation, Doha, Qatar.ORCID 0000-0001-9009-0641
Mohamed Omar SaadPharmacy Department, Hamad Medical Corporation, Doha, Qatar.ORCID 0000-0002-2221-4216
Islam EljilanyDepartment of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.ORCID 0000-0001-6387-5419
Loulia BaderCollege of Pharmacy, QU Health, Qatar University, Doha, Qatar.ORCID 0000-0001-9276-6959
Hazem ElewaCollege of Pharmacy, QU Health, Qatar University, Doha, Qatar.ORCID 0000-0003-1594-1199

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundPrevious studies demonstrated the superiority of a genotype-guided warfarin dosing (GWD) method for warfarin initiation. International GWD models such as Gage et al model were validated in diverse populations but Arab patients were not well represented in these studies.ObjectiveTo derive and validate a GWD model in an Arab population and compare the outcomes to Gage et al model.MethodsIn this cross-sectional study, DNA was collected through saliva kits from a cohort of recruited Arab patients on warfarin

Indexed as

AnticoagulantsWarfarinAdultArabsCross-Sectional StudiesCytochrome P-450 CYP2C9FemaleGenotypeHumansMaleMiddle AgedVitamin K Epoxide ReductasesAnticoagulantsCytochrome P-450 CYP2C9Vitamin K Epoxide ReductasesWarfaringenotype guided dosing –model derivation - model validation – warfarin dosing – precision dosing

Identifiers

PMID42262158
PMCPMC13250413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.