Evidence map›Paper›PMID 42262080›Full record

ArticleMicrobiology spectrum2026

The mycobacterial nucleoid-associated protein NapM exhibits stress-induced septal localization and modulates cell envelope gene expression.

Kornel Milcarz, Joanna Hołówka, Jakub Pawełczyk, Mariola Paściak, Yaroslav Lavrynchuk, Michał Tracz, Przemysław Płociński, Jolanta Zakrzewska-Czerwińska

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In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kornel MilcarzDepartment of Molecular Microbiology, University of Wrocław, Wrocław, Poland.ORCID 0000-0003-4917-5680
Joanna HołówkaDepartment of Molecular Microbiology, University of Wrocław, Wrocław, Poland.ORCID 0000-0002-8880-2854
Jakub PawełczykLaboratory of Genetics and Physiology of Mycobacterium, Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.
Mariola PaściakDepartment of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.ORCID 0000-0002-2603-4634
Yaroslav LavrynchukBio-Med-Chem Doctoral School of the University of Łódź and Łódź Institutes of the Polish Academy of Sciences, Faculty of Biology and Environmental Protection, University of Łódź, Łódź, Poland.
Michał TraczProtein Mass Spectrometry Laboratory, University of Wrocław, Wrocław, Poland.
Przemysław PłocińskiDepartment of Immunology and Infectious Biology, Faculty of Biology and Environmental Protection, University of Łódź, Łódź, Poland.
Jolanta Zakrzewska-CzerwińskaDepartment of Molecular Microbiology, University of Wrocław, Wrocław, Poland.ORCID 0000-0002-2042-974X

Funding

Narodowe Centrum Nauki 2020/37/B/NZ1/00556
6 · The paper itself

Abstract

The bacterial chromosome is organized in a hierarchical and dynamic manner to facilitate essential DNA transactions. Nucleoid-associated proteins (NAPs) are abundant, small-scale chromosomal organizers that also play important roles in maintaining chromosomal DNA integrity, regulating gene expression and DNA replication, and facilitating DNA repair. Here, we show that under optimal growth conditions, NapM-a unique mycobacterial NAP-modulates the expression of nearly one-sixth of IMPORTANCE: Understanding how bacteria adapt to environmental stress is critical to combating antibiotic resistance. This study characterizes NapM, a stress-responsive nucleoid-associated protein (NAP) in

Indexed as

Bacterial ProteinsCell MembraneCell WallDNA-Binding ProteinsMycobacterium smegmatisCell Cycle ProteinsCell DivisionChromosomes, BacterialGene Expression Regulation, BacterialStress, PhysiologicalBacterial ProteinsCell Cycle ProteinsDivIVA protein, bacteriaDNA-Binding Proteinscell cyclecell divisionmicrobiologymycobacteriumnucleoid-associated proteinstranscriptome

Identifiers

PMID42262080
PMCPMC13340245

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.