ArticleJournal of the American Heart Association2026
Diagnostic Trends and Geographic Health Care Disparities Among Patients With Transthyretin Amyloid Cardiomyopathy.
Article in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Cardiac Amyloidosis: A Field Transformed and the Work That Remains.JACC. Case reports · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransthyretin amyloid cardiomyopathy (ATTR-CM) is a rare, life-threatening form of restrictive cardiomyopathy. Access to cardiology providers and specialized amyloid centers may impact ATTR-CM diagnosis. We sought to elucidate diagnostic disparities of ATTR-CM through assessment of diagnostic trends and the geographic distribution of amyloid centers and cardiology providers in the United States.
methodsThis was a cross-sectional geospatial analysis of amyloid centers and cardiology providers and a retrospective cohort analysis of patients with ATTR-CM from the Komodo Healthcare Map from July 1, 2016, to June 30, 2024.
resultsAmong 14 980 patients, mean age was 74.8 years, 62.3% were men, 54.1% were White individuals, and 28.8% were Black individuals. The diagnosed prevalence of ATTR-CM was 35.68 per 100 000 persons. Prevalence was highest in Black patients (102.17) and in the Northeast (52.63), and it increased 4-fold over the study period. Mean distance of patients to a cardiology provider was 4.3 miles and to an amyloid center was 48.5 miles. Large areas of the country, particularly in the Midwest, were identified with limited cardiology providers and amyloid centers.
conclusionsThe prevalence of ATTR-CM has increased substantially since 2017, with notable racial differences; however, there remain geographic disparities. Strategies to address these regional disparities need to be identified.
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